ENSG00000153898


Homo sapiens

Features
Gene ID: ENSG00000153898
  
Biological name :MCOLN2
  
Synonyms : MCOLN2 / mucolipin 2 / Q8IZK6
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: -1
Band: p22.3
Gene start: 84925583
Gene end: 84997113
  
Corresponding Affymetrix probe sets: 1555465_at (Human Genome U133 Plus 2.0 Array)   230110_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000284027
Ensembl peptide - ENSP00000359640
Ensembl peptide - ENSP00000436299
NCBI entrez gene - 255231     See in Manteia.
OMIM - 607399
RefSeq - XM_017000923
RefSeq - NM_153259
RefSeq - XM_005270719
RefSeq - XM_006710552
RefSeq - XM_011541187
RefSeq - XM_011541188
RefSeq Peptide - NP_001317576
RefSeq Peptide - NP_694991
swissprot - Q8IZK6
swissprot - G5EA24
Ensembl - ENSG00000153898
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 mcoln2ENSDARG00000098918Danio rerio
 MCOLN2ENSGALG00000008722Gallus gallus
 Mcoln2ENSMUSG00000011008Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
MCOLN3 / Q8TDD5 / mucolipin 3ENSG0000005573253
MCOLN1 / Q9GZU1 / mucolipin 1ENSG0000009067446


Protein motifs (from Interpro)
Interpro ID Name
 IPR013122  Polycystin cation channel, PKD1/PKD2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002250 adaptive immune response IEA
 biological_processGO:0002376 immune system process IEA
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006816 calcium ion transport IEA
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0032722 positive regulation of chemokine production IEA
 biological_processGO:0035926 chemokine (C-C motif) ligand 2 secretion IEA
 biological_processGO:0045087 innate immune response IEA
 biological_processGO:0051259 protein complex oligomerization IEA
 biological_processGO:0070588 calcium ion transmembrane transport TAS
 biological_processGO:0071639 positive regulation of monocyte chemotactic protein-1 production IEA
 biological_processGO:0071642 positive regulation of macrophage inflammatory protein 1 alpha production IEA
 biological_processGO:0071651 positive regulation of chemokine (C-C motif) ligand 5 production IEA
 biological_processGO:1905517 macrophage migration IEA
 biological_processGO:1990266 neutrophil migration IEA
 biological_processGO:2000343 positive regulation of chemokine (C-X-C motif) ligand 2 production IEA
 cellular_componentGO:0005764 lysosome IEA
 cellular_componentGO:0005765 lysosomal membrane IEA
 cellular_componentGO:0005768 endosome IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0031902 late endosome membrane IEA
 cellular_componentGO:0055037 recycling endosome IEA
 cellular_componentGO:0055038 recycling endosome membrane IEA
 molecular_functionGO:0005262 calcium channel activity TAS


Pathways (from Reactome)
Pathway description
TRP channels


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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