ENSG00000153936


Homo sapiens

Features
Gene ID: ENSG00000153936
  
Biological name :HS2ST1
  
Synonyms : heparan sulfate 2-O-sulfotransferase 1 / HS2ST1 / Q7LGA3
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: 1
Band: p22.3
Gene start: 86914648
Gene end: 87109998
  
Corresponding Affymetrix probe sets: 203283_s_at (Human Genome U133 Plus 2.0 Array)   203284_s_at (Human Genome U133 Plus 2.0 Array)   203285_s_at (Human Genome U133 Plus 2.0 Array)   230465_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000359582
Ensembl peptide - ENSP00000359581
Ensembl peptide - ENSP00000467253
NCBI entrez gene - 9653     See in Manteia.
OMIM - 604844
RefSeq - NM_012262
RefSeq - NM_001134492
RefSeq Peptide - NP_001127964
RefSeq Peptide - NP_036394
swissprot - Q7LGA3
swissprot - K7EP71
Ensembl - ENSG00000153936
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 hs2st1aENSDARG00000099478Danio rerio
 hs2st1bENSDARG00000062008Danio rerio
 HS2ST1ENSGALG00000028423Gallus gallus
 Hs2st1ENSMUSG00000040151Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
AC093155.3ENSG0000026756168
UST / Q9Y2C2 / uronyl 2-sulfotransferaseENSG0000011196226


Protein motifs (from Interpro)
Interpro ID Name
 IPR005331  Sulfotransferase
 IPR007734  Heparan sulphate 2-O-sulfotransferase
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006024 glycosaminoglycan biosynthetic process TAS
 cellular_componentGO:0000139 Golgi membrane TAS
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004394 heparan sulfate 2-O-sulfotransferase activity TAS
 molecular_functionGO:0008146 sulfotransferase activity IEA
 molecular_functionGO:0016740 transferase activity IEA


Pathways (from Reactome)
Pathway description
HS-GAG biosynthesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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