ENSG00000154096


Homo sapiens

Features
Gene ID: ENSG00000154096
  
Biological name :THY1
  
Synonyms : P04216 / THY1 / Thy-1 cell surface antigen
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 11
Strand: -1
Band: q23.3
Gene start: 119417378
Gene end: 119424985
  
Corresponding Affymetrix probe sets: 208850_s_at (Human Genome U133 Plus 2.0 Array)   208851_s_at (Human Genome U133 Plus 2.0 Array)   213869_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000435753
Ensembl peptide - ENSP00000284240
Ensembl peptide - ENSP00000464248
Ensembl peptide - ENSP00000431301
Ensembl peptide - ENSP00000432808
Ensembl peptide - ENSP00000432051
NCBI entrez gene - 7070     See in Manteia.
OMIM - 188230
RefSeq - NM_001311162
RefSeq - NM_006288
RefSeq - NM_001311160
RefSeq Peptide - NP_001298089
RefSeq Peptide - NP_001298091
RefSeq Peptide - NP_006279
swissprot - P04216
swissprot - E9PIM6
swissprot - E9PIE1
swissprot - B0YJA4
swissprot - J3QRJ3
swissprot - E9PNQ8
Ensembl - ENSG00000154096
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 THY1ENSGALG00000006751Gallus gallus
 Thy1ENSMUSG00000032011Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR007110  Immunoglobulin-like domain
 IPR013106  Immunoglobulin V-set domain
 IPR013151  Immunoglobulin
 IPR013783  Immunoglobulin-like fold
 IPR033292  Thy-1 membrane glycoprotein
 IPR036179  Immunoglobulin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001525 angiogenesis IBA
 biological_processGO:0001952 regulation of cell-matrix adhesion IMP
 biological_processGO:0002693 positive regulation of cellular extravasation IDA
 biological_processGO:0006469 negative regulation of protein kinase activity ISS
 biological_processGO:0006501 C-terminal protein lipidation TAS
 biological_processGO:0007010 cytoskeleton organization IBA
 biological_processGO:0007155 cell adhesion IEA
 biological_processGO:0007229 integrin-mediated signaling pathway IMP
 biological_processGO:0007267 cell-cell signaling ISS
 biological_processGO:0030334 regulation of cell migration IEA
 biological_processGO:0030336 negative regulation of cell migration IBA
 biological_processGO:0034116 positive regulation of heterotypic cell-cell adhesion IDA
 biological_processGO:0043113 receptor clustering ISS
 biological_processGO:0043547 positive regulation of GTPase activity ISS
 biological_processGO:0046549 retinal cone cell development IBA
 biological_processGO:0046777 protein autophosphorylation IEA
 biological_processGO:0048041 focal adhesion assembly ISS
 biological_processGO:0050771 negative regulation of axonogenesis IBA
 biological_processGO:0050852 T cell receptor signaling pathway IBA
 biological_processGO:0050860 negative regulation of T cell receptor signaling pathway ISS
 biological_processGO:0050870 positive regulation of T cell activation IBA
 biological_processGO:0051281 positive regulation of release of sequestered calcium ion into cytosol IBA
 biological_processGO:0051894 positive regulation of focal adhesion assembly IMP
 biological_processGO:0061099 negative regulation of protein tyrosine kinase activity ISS
 biological_processGO:0070571 negative regulation of neuron projection regeneration ISS
 biological_processGO:0098609 cell-cell adhesion ISS
 biological_processGO:2000298 regulation of Rho-dependent protein serine/threonine kinase activity ISS
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005783 endoplasmic reticulum IDA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005886 plasma membrane NAS
 cellular_componentGO:0005887 integral component of plasma membrane TAS
 cellular_componentGO:0005925 focal adhesion HDA
 cellular_componentGO:0009897 external side of plasma membrane ISS
 cellular_componentGO:0009986 cell surface IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016324 apical plasma membrane IDA
 cellular_componentGO:0030425 dendrite IBA
 cellular_componentGO:0030426 growth cone ISS
 cellular_componentGO:0030673 axolemma ISS
 cellular_componentGO:0031225 anchored component of membrane IEA
 cellular_componentGO:0031362 anchored component of external side of plasma membrane IBA
 cellular_componentGO:0032590 dendrite membrane ISS
 cellular_componentGO:0032809 neuronal cell body membrane ISS
 cellular_componentGO:0043209 myelin sheath IBA
 cellular_componentGO:0045121 membrane raft IBA
 cellular_componentGO:0046658 anchored component of plasma membrane IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0005096 GTPase activator activity IBA
 molecular_functionGO:0005178 integrin binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0019899 enzyme binding IEA
 molecular_functionGO:0019901 protein kinase binding IBA
 molecular_functionGO:0034235 GPI anchor binding IBA


Pathways (from Reactome)
Pathway description
Post-translational modification: synthesis of GPI-anchored proteins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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