ENSMUSG00000032011


Mus musculus

Features
Gene ID: ENSMUSG00000032011
  
Biological name :Thy1
  
Synonyms : P01831 / Thy1 / Thy-1 membrane glycoprotein
  
Possible biological names infered from orthology : P04216 / Thy-1 cell surface antigen
  
Species: Mus musculus
  
Chr. number: 9
Strand: 1
Band: A5.1
Gene start: 44043384
Gene end: 44048579
  
Corresponding Affymetrix probe sets: 10584628 (MoGene1.0st)   1423135_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000110489
Ensembl peptide - ENSMUSP00000150960
Ensembl peptide - ENSMUSP00000150177
Ensembl peptide - ENSMUSP00000149610
NCBI entrez gene - 21838     See in Manteia.
MGI - MGI:98747
RefSeq - NM_009382
RefSeq Peptide - NP_033408
swissprot - A0A1L1ST40
swissprot - A0A1L1SRS7
swissprot - A0A1L1SUX8
swissprot - P01831
Ensembl - ENSMUSG00000032011
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 THY1ENSGALG00000006751Gallus gallus
 THY1ENSG00000154096Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR007110  Immunoglobulin-like domain
 IPR013106  Immunoglobulin V-set domain
 IPR013151  Immunoglobulin
 IPR013783  Immunoglobulin-like fold
 IPR033292  Thy-1 membrane glycoprotein
 IPR036179  Immunoglobulin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001525 angiogenesis IDA
 biological_processGO:0001952 regulation of cell-matrix adhesion IEA
 biological_processGO:0002693 positive regulation of cellular extravasation IEA
 biological_processGO:0006469 negative regulation of protein kinase activity IEA
 biological_processGO:0007010 cytoskeleton organization IEA
 biological_processGO:0007155 cell adhesion IEA
 biological_processGO:0007229 integrin-mediated signaling pathway IEA
 biological_processGO:0007267 cell-cell signaling IEA
 biological_processGO:0030334 regulation of cell migration IEA
 biological_processGO:0030336 negative regulation of cell migration IEA
 biological_processGO:0034116 positive regulation of heterotypic cell-cell adhesion IEA
 biological_processGO:0043113 receptor clustering IEA
 biological_processGO:0043547 positive regulation of GTPase activity IEA
 biological_processGO:0046549 retinal cone cell development IMP
 biological_processGO:0046777 protein autophosphorylation IEA
 biological_processGO:0048041 focal adhesion assembly IEA
 biological_processGO:0050771 negative regulation of axonogenesis IEA
 biological_processGO:0050852 T cell receptor signaling pathway IEA
 biological_processGO:0050860 negative regulation of T cell receptor signaling pathway IDA
 biological_processGO:0050870 positive regulation of T cell activation IEA
 biological_processGO:0051281 positive regulation of release of sequestered calcium ion into cytosol IEA
 biological_processGO:0051894 positive regulation of focal adhesion assembly IEA
 biological_processGO:0061099 negative regulation of protein tyrosine kinase activity IEA
 biological_processGO:0070571 negative regulation of neuron projection regeneration IMP
 biological_processGO:0098609 cell-cell adhesion IEA
 biological_processGO:2000298 regulation of Rho-dependent protein serine/threonine kinase activity IDA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005886 plasma membrane ISS
 cellular_componentGO:0009897 external side of plasma membrane IDA
 cellular_componentGO:0009986 cell surface IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016324 apical plasma membrane IEA
 cellular_componentGO:0030425 dendrite IDA
 cellular_componentGO:0030426 growth cone IEA
 cellular_componentGO:0030673 axolemma IEA
 cellular_componentGO:0031225 anchored component of membrane IEA
 cellular_componentGO:0031362 anchored component of external side of plasma membrane IDA
 cellular_componentGO:0032590 dendrite membrane IEA
 cellular_componentGO:0032809 neuronal cell body membrane IEA
 cellular_componentGO:0043209 myelin sheath IDA
 cellular_componentGO:0045121 membrane raft IEA
 cellular_componentGO:0046658 anchored component of plasma membrane IEA
 molecular_functionGO:0005096 GTPase activator activity IEA
 molecular_functionGO:0005178 integrin binding IEA
 molecular_functionGO:0019899 enzyme binding IEA
 molecular_functionGO:0019901 protein kinase binding IEA
 molecular_functionGO:0034235 GPI anchor binding IEA


Pathways (from Reactome)
Pathway description
Post-translational modification: synthesis of GPI-anchored proteins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001473 reduced long term potentiation "less than the normal persistent robust synaptic response induced by synchronous stimulation of pre- and postsynaptic cells " [Principles of Neural Science:ISBN 0-8385-8034-3]
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Allelic Composition: Pafah1b1tm1Awb/Pafah1b1+
Genetic Background: involves: 129S6/SvEvTac

 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: MitfMi-b/Mitf+
Genetic Background: involves: 101/Rl * C3H/Rl

 MP:0006050 pulmonary fibrosis "formation of fibrous tissue within the lung often resulting from inflammation or injury " [RGD:Rat Genome Database submission, smb:Susan M Bello, Mouse Genome Informatics Curator]
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Allelic Composition: Pafah1b1tm1Awb/Pafah1b1+
Genetic Background: involves: 129S6/SvEvTac

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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