ENSG00000154127


Homo sapiens

Features
Gene ID: ENSG00000154127
  
Biological name :UBASH3B
  
Synonyms : Q8TF42 / UBASH3B / ubiquitin associated and SH3 domain containing B
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 11
Strand: 1
Band: q24.1
Gene start: 122655675
Gene end: 122814473
  
Corresponding Affymetrix probe sets: 228353_x_at (Human Genome U133 Plus 2.0 Array)   228359_at (Human Genome U133 Plus 2.0 Array)   238462_at (Human Genome U133 Plus 2.0 Array)   238587_at (Human Genome U133 Plus 2.0 Array)   240387_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000284273
NCBI entrez gene - 84959     See in Manteia.
OMIM - 609201
RefSeq - XM_011543042
RefSeq - NM_032873
RefSeq - XM_005271712
RefSeq - XM_011543041
RefSeq Peptide - NP_116262
swissprot - Q8TF42
Ensembl - ENSG00000154127
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ubash3baENSDARG00000061243Danio rerio
 ubash3bbENSDARG00000077399Danio rerio
 UBASH3BENSGALG00000006567Gallus gallus
 Q8BGG7ENSMUSG00000032020Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
P57075 / UBASH3A / ubiquitin associated and SH3 domain containing AENSG0000016018544


Protein motifs (from Interpro)
Interpro ID Name
 IPR001452  SH3 domain
 IPR009060  UBA-like superfamily
 IPR009097  Cyclic phosphodiesterase
 IPR013078  Histidine phosphatase superfamily, clade-1
 IPR015940  Ubiquitin-associated domain
 IPR029033  Histidine phosphatase superfamily
 IPR035632  UBASH3B, SH3 domain
 IPR036028  SH3-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006469 negative regulation of protein kinase activity IEA
 biological_processGO:0009968 negative regulation of signal transduction IEA
 biological_processGO:0030168 platelet activation IEA
 biological_processGO:0035335 peptidyl-tyrosine dephosphorylation IEA
 biological_processGO:0038063 collagen-activated tyrosine kinase receptor signaling pathway IEA
 biological_processGO:0038065 collagen-activated signaling pathway IEA
 biological_processGO:0043393 regulation of protein binding IEA
 biological_processGO:0045670 regulation of osteoclast differentiation IEA
 biological_processGO:0045671 negative regulation of osteoclast differentiation IEA
 biological_processGO:0045779 negative regulation of bone resorption IEA
 biological_processGO:0051279 regulation of release of sequestered calcium ion into cytosol IEA
 biological_processGO:0070527 platelet aggregation IEA
 biological_processGO:0090331 negative regulation of platelet aggregation IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0004721 phosphoprotein phosphatase activity IEA
 molecular_functionGO:0004725 protein tyrosine phosphatase activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0031625 ubiquitin protein ligase binding IEA
 molecular_functionGO:0042802 identical protein binding IPI
 molecular_functionGO:0051219 phosphoprotein binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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