ENSG00000154305


Homo sapiens

Features
Gene ID: ENSG00000154305
  
Biological name :MIA3
  
Synonyms : MIA3 / MIA family member 3, ER export factor / Q5JRA6
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: 1
Band: q41
Gene start: 222618086
Gene end: 222668012
  
Corresponding Affymetrix probe sets: 1569057_s_at (Human Genome U133 Plus 2.0 Array)   212305_s_at (Human Genome U133 Plus 2.0 Array)   212310_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000340900
Ensembl peptide - ENSP00000345866
Ensembl peptide - ENSP00000355062
Ensembl peptide - ENSP00000396598
Ensembl peptide - ENSP00000341348
NCBI entrez gene - 375056     See in Manteia.
OMIM - 613455
RefSeq - XM_017001243
RefSeq - NM_001300867
RefSeq - NM_001324062
RefSeq - NM_001324063
RefSeq - NM_001324064
RefSeq - NM_001324065
RefSeq - NM_198551
RefSeq - XM_006711304
RefSeq - XM_011509513
RefSeq Peptide - NP_001287796
RefSeq Peptide - NP_001310994
RefSeq Peptide - NP_940953
RefSeq Peptide - NP_001310991
RefSeq Peptide - NP_001310992
RefSeq Peptide - NP_001310993
swissprot - H7C0T4
swissprot - Q5JRA6
swissprot - A0A0A0MRH6
Ensembl - ENSG00000154305
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 mia3ENSDARG00000008184Danio rerio
 MIA3ENSGALG00000041034Gallus gallus
 Mia3ENSMUSG00000056050Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CTAGE5 / O15320 / Q96PC5 / CTAGE family member 5, ER export factorENSG0000015052712
A4FU28 / CTAGE9 / CTAGE family member 9ENSG0000023676111
CTAGE4 / Q8IX94 / CTAGE family member 4ENSG0000022593211
CTAGE8 / P0CG41 / CTAGE family member 8ENSG0000024469311
A4D2H0 / CTAGE15 / CTAGE family member 15ENSG0000027107911
CTAGE6 / Q86UF2 / CTAGE family member 6ENSG0000027132111
CTAGE1 / Q96RT6 / Q9HC47 / cutaneous T cell lymphoma-associated antigen 1ENSG0000021271010


Protein motifs (from Interpro)
Interpro ID Name
 IPR001452  SH3 domain
 IPR036028  SH3-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002687 positive regulation of leukocyte migration IDA
 biological_processGO:0006887 exocytosis IMP
 biological_processGO:0006888 ER to Golgi vesicle-mediated transport TAS
 biological_processGO:0007162 negative regulation of cell adhesion IDA
 biological_processGO:0015031 protein transport IMP
 biological_processGO:0016192 vesicle-mediated transport IEA
 biological_processGO:0030336 negative regulation of cell migration IDA
 biological_processGO:0042060 wound healing IDA
 biological_processGO:0042953 lipoprotein transport IMP
 biological_processGO:0043687 post-translational protein modification TAS
 biological_processGO:0044267 cellular protein metabolic process TAS
 biological_processGO:0090110 cargo loading into COPII-coated vesicle IMP
 cellular_componentGO:0000139 Golgi membrane IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005788 endoplasmic reticulum lumen TAS
 cellular_componentGO:0005789 endoplasmic reticulum membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IDA
 cellular_componentGO:0070971 endoplasmic reticulum exit site IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0042954 lipoprotein transporter activity IMP


Pathways (from Reactome)
Pathway description
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
Cargo concentration in the ER
Post-translational protein phosphorylation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000138073 PREB / Q9HCU5 / prolactin regulatory element binding  / reaction / complex
 ENSG00000150527 CTAGE5 / O15320 / Q96PC5 / CTAGE family member 5, ER export factor  / complex / reaction
 ENSG00000100934 Q15436 / SEC23A / Sec23 homolog A, coat complex II component  / complex / reaction
 ENSG00000176986 P53992 / SEC24C / SEC24 homolog C, COPII coat complex component  / complex / reaction






 

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