ENSG00000154813


Homo sapiens

Features
Gene ID: ENSG00000154813
  
Biological name :DPH3
  
Synonyms : diphthamide biosynthesis 3 / DPH3 / Q96FX2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 3
Strand: -1
Band: p25.1
Gene start: 16257978
Gene end: 16264972
  
Corresponding Affymetrix probe sets: 225195_at (Human Genome U133 Plus 2.0 Array)   225200_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000419599
Ensembl peptide - ENSP00000373285
NCBI entrez gene - 285381     See in Manteia.
OMIM - 608959
RefSeq - NM_001047434
RefSeq - NM_206831
RefSeq Peptide - NP_001040899
RefSeq Peptide - NP_996662
swissprot - Q96FX2
swissprot - A0A024R2P5
Ensembl - ENSG00000154813
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 dph3ENSDARG00000043360Danio rerio
 DPH3ENSGALG00000011237Gallus gallus
 Dph3ENSMUSG00000021905Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR007872  Zinc finger, DPH-type
 IPR036671  DPH Zinc finger superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0017183 peptidyl-diphthamide biosynthetic process from peptidyl-histidine TAS
 biological_processGO:0050709 negative regulation of protein secretion IDA
 biological_processGO:0051099 positive regulation of binding IDA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Synthesis of diphthamide-EEF2


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000108963 DPH1 / Q9BZG8 / diphthamide biosynthesis 1  / complex
 ENSG00000132768 DPH2 / Q9BQC3 / DPH2 homolog  / complex






 

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