ENSG00000155252


Homo sapiens

Features
Gene ID: ENSG00000155252
  
Biological name :PI4K2A
  
Synonyms : phosphatidylinositol 4-kinase type 2 alpha / PI4K2A / Q9BTU6
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 10
Strand: 1
Band: q24.2
Gene start: 97640686
Gene end: 97676434
  
Corresponding Affymetrix probe sets: 209345_s_at (Human Genome U133 Plus 2.0 Array)   209346_s_at (Human Genome U133 Plus 2.0 Array)   215134_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000359665
NCBI entrez gene - 55361     See in Manteia.
OMIM - 609763
RefSeq - NM_018425
RefSeq Peptide - NP_060895
swissprot - Q9BTU6
Ensembl - ENSG00000155252
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 pi4k2aENSDARG00000033666Danio rerio
 ENSGALG00000006143Gallus gallus
 Pi4k2aENSMUSG00000025178Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
AL355315.1ENSG0000024996772
PI4K2B / Q8TCG2 / phosphatidylinositol 4-kinase type 2 betaENSG0000003821057
AC104662.2ENSG0000028102855


Protein motifs (from Interpro)
Interpro ID Name
 IPR000403  Phosphatidylinositol 3-/4-kinase, catalytic domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002561 basophil degranulation IEA
 biological_processGO:0006661 phosphatidylinositol biosynthetic process IDA
 biological_processGO:0007030 Golgi organization IBA
 biological_processGO:0007032 endosome organization IBA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0046854 phosphatidylinositol phosphorylation IDA
 cellular_componentGO:0005739 mitochondrion ISS
 cellular_componentGO:0005765 lysosomal membrane HDA
 cellular_componentGO:0005768 endosome IBA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005802 trans-Golgi network IBA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005887 integral component of plasma membrane IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0030425 dendrite ISS
 cellular_componentGO:0030672 synaptic vesicle membrane IEA
 cellular_componentGO:0031083 BLOC-1 complex IDA
 cellular_componentGO:0031224 intrinsic component of membrane IDA
 cellular_componentGO:0031410 cytoplasmic vesicle ISS
 cellular_componentGO:0031901 early endosome membrane IEA
 cellular_componentGO:0035838 growing cell tip IEA
 cellular_componentGO:0042734 presynaptic membrane ISS
 cellular_componentGO:0042995 cell projection IEA
 cellular_componentGO:0043005 neuron projection ISS
 cellular_componentGO:0043025 neuronal cell body IEA
 cellular_componentGO:0043204 perikaryon IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IEA
 cellular_componentGO:0044231 host cell presynaptic membrane IEA
 cellular_componentGO:0045121 membrane raft IEA
 cellular_componentGO:0045202 synapse IEA
 cellular_componentGO:0070382 exocytic vesicle IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0000287 magnesium ion binding NAS
 molecular_functionGO:0004430 1-phosphatidylinositol 4-kinase activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0035651 AP-3 adaptor complex binding IDA


Pathways (from Reactome)
Pathway description
Synthesis of PIPs at the plasma membrane
Synthesis of PIPs at the Golgi membrane
Synthesis of PIPs at the early endosome membrane


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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