ENSG00000156575


Homo sapiens

Features
Gene ID: ENSG00000156575
  
Biological name :PRG3
  
Synonyms : PRG3 / proteoglycan 3, pro eosinophil major basic protein 2 / Q9Y2Y8
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 11
Strand: -1
Band: q12.1
Gene start: 57376769
Gene end: 57381150
  
Corresponding Affymetrix probe sets: 220811_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000287143
NCBI entrez gene - 10394     See in Manteia.
OMIM - 606814
RefSeq - NM_006093
RefSeq Peptide - NP_006084
swissprot - Q9Y2Y8
Ensembl - ENSG00000156575
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PGR2/3ENSGALG00000043860Gallus gallus
 Prg3ENSMUSG00000027072Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PRG2 / P13727 / proteoglycan 2, pro eosinophil major basic proteinENSG0000018665247


Protein motifs (from Interpro)
Interpro ID Name
 IPR001304  C-type lectin-like
 IPR002352  Eosinophil major basic protein
 IPR016186  C-type lectin-like/link domain superfamily
 IPR016187  C-type lectin fold
 IPR018378  C-type lectin, conserved site
 IPR033816  Eosinophil major basic protein, C-type lectin-like domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001694 histamine biosynthetic process IDA
 biological_processGO:0006955 immune response IEA
 biological_processGO:0017148 negative regulation of translation IDA
 biological_processGO:0019370 leukotriene biosynthetic process IDA
 biological_processGO:0042119 neutrophil activation IDA
 biological_processGO:0042554 superoxide anion generation IDA
 biological_processGO:0043312 neutrophil degranulation TAS
 biological_processGO:0045416 positive regulation of interleukin-8 biosynthetic process IDA
 biological_processGO:0045575 basophil activation IDA
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0035580 specific granule lumen TAS
 cellular_componentGO:1904724 tertiary granule lumen TAS
 molecular_functionGO:0030246 carbohydrate binding IEA


Pathways (from Reactome)
Pathway description
Neutrophil degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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