ENSG00000158417


Homo sapiens

Features
Gene ID: ENSG00000158417
  
Biological name :EIF5B
  
Synonyms : EIF5B / eukaryotic translation initiation factor 5B / O60841
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 2
Strand: 1
Band: q11.2
Gene start: 99337353
Gene end: 99401326
  
Corresponding Affymetrix probe sets: 201024_x_at (Human Genome U133 Plus 2.0 Array)   201025_at (Human Genome U133 Plus 2.0 Array)   201026_at (Human Genome U133 Plus 2.0 Array)   201027_s_at (Human Genome U133 Plus 2.0 Array)   214313_s_at (Human Genome U133 Plus 2.0 Array)   214314_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000289371
Ensembl peptide - ENSP00000478914
NCBI entrez gene - 9669     See in Manteia.
OMIM - 606086
RefSeq - NM_015904
RefSeq Peptide - NP_056988
swissprot - A0A087WUT6
swissprot - O60841
Ensembl - ENSG00000158417
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 eif5bENSDARG00000016548Danio rerio
 EIF5BENSGALG00000016764Gallus gallus
 Eif5bENSMUSG00000026083Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000795  Transcription factor, GTP-binding domain
 IPR004161  Translation elongation factor EFTu-like, domain 2
 IPR005225  Small GTP-binding protein domain
 IPR009000  Translation protein, beta-barrel domain superfamily
 IPR015760  Translation initiation factor IF- 2
 IPR023115  Translation initiation factor IF- 2, domain 3
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR036925  Translation initiation factor IF-2, domain 3 superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006412 translation IEA
 biological_processGO:0006413 translational initiation IEA
 biological_processGO:0006446 regulation of translational initiation NAS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003723 RNA binding HDA
 molecular_functionGO:0003743 translation initiation factor activity NAS
 molecular_functionGO:0003924 GTPase activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005525 GTP binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
GTP hydrolysis and joining of the 60S ribosomal subunit


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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