ENSG00000159069


Homo sapiens

Features
Gene ID: ENSG00000159069
  
Biological name :FBXW5
  
Synonyms : F-box and WD repeat domain containing 5 / FBXW5 / Q969U6
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 9
Strand: -1
Band: q34.3
Gene start: 136940435
Gene end: 136944696
  
Corresponding Affymetrix probe sets: 223050_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000313034
Ensembl peptide - ENSP00000485322
Ensembl peptide - ENSP00000485109
Ensembl peptide - ENSP00000404829
Ensembl peptide - ENSP00000394011
NCBI entrez gene - 54461     See in Manteia.
OMIM - 609072
RefSeq - XM_017014812
RefSeq - NM_018998
RefSeq - XM_005266089
RefSeq - XM_011518789
RefSeq Peptide - NP_061871
swissprot - A0A0A0MSV8
swissprot - A0A0A0MSK7
swissprot - A0A096LP04
swissprot - A0A096LNM2
swissprot - A0A024R8H7
swissprot - Q969U6
Ensembl - ENSG00000159069
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 fbxw5ENSDARG00000099139Danio rerio
 FBXW5ENSGALG00000030831Gallus gallus
 Fbxw5ENSMUSG00000015095Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001680  WD40 repeat
 IPR001810  F-box domain
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR017986  WD40-repeat-containing domain
 IPR036047  F-box-like domain superfamily
 IPR036322  WD40-repeat-containing domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000209 protein polyubiquitination TAS
 biological_processGO:0007088 regulation of mitotic nuclear division IEA
 biological_processGO:0010824 regulation of centrosome duplication IMP
 biological_processGO:0016567 protein ubiquitination IEA
 biological_processGO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process IDA
 biological_processGO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process IDA
 biological_processGO:0043687 post-translational protein modification TAS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0019005 SCF ubiquitin ligase complex IDA
 cellular_componentGO:0080008 Cul4-RING E3 ubiquitin ligase complex IDA
 molecular_functionGO:0004842 ubiquitin-protein transferase activity TAS
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0019901 protein kinase binding IPI


Pathways (from Reactome)
Pathway description
Association of TriC/CCT with target proteins during biosynthesis
Neddylation
Antigen processing: Ubiquitination & Proteasome degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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