ENSG00000159723


Homo sapiens

Features
Gene ID: ENSG00000159723
  
Biological name :AGRP
  
Synonyms : agouti related neuropeptide / AGRP / O00253
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 16
Strand: -1
Band: q22.1
Gene start: 67482571
Gene end: 67483813
  
Corresponding Affymetrix probe sets: 207193_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000290953
NCBI entrez gene - 181     See in Manteia.
OMIM - 602311
RefSeq - NM_001138
RefSeq Peptide - NP_001129
swissprot - C6SUN5
swissprot - O00253
Ensembl - ENSG00000159723
  
Related genetic diseases (OMIM): 601665 - {Obesity, late-onset}, 601665
  602311 - {Leanness, inherited}
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 agrpENSDARG00000069089Danio rerio
 AGRPENSGALG00000002244Gallus gallus
 AgrpENSMUSG00000005705Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR007733  Agouti
 IPR027300  Agouti domain
 IPR036836  Agouti domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007218 neuropeptide signaling pathway TAS
 biological_processGO:0007623 circadian rhythm IEA
 biological_processGO:0007631 feeding behavior TAS
 biological_processGO:0008343 adult feeding behavior IEA
 biological_processGO:0009755 hormone-mediated signaling pathway IEA
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0032868 response to insulin IEA
 biological_processGO:0042755 eating behavior IEA
 biological_processGO:0048571 long-day photoperiodism IEA
 biological_processGO:0060135 maternal process involved in female pregnancy IEA
 biological_processGO:0060259 regulation of feeding behavior IMP
 biological_processGO:2000253 positive regulation of feeding behavior IEA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005796 Golgi lumen IEA
 cellular_componentGO:0043025 neuronal cell body IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0005102 signaling receptor binding TAS
 molecular_functionGO:0005184 neuropeptide hormone activity TAS


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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