ENSG00000160233


Homo sapiens

Features
Gene ID: ENSG00000160233
  
Biological name :LRRC3
  
Synonyms : leucine rich repeat containing 3 / LRRC3 / Q9BY71
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 21
Strand: 1
Band: q22.3
Gene start: 44455486
Gene end: 44462196
  
Corresponding Affymetrix probe sets: 221017_s_at (Human Genome U133 Plus 2.0 Array)   232536_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000291592
NCBI entrez gene - 81543     See in Manteia.
OMIM - 617620
RefSeq - NM_030891
RefSeq Peptide - NP_112153
swissprot - Q9BY71
Ensembl - ENSG00000160233
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 lrrc3ENSDARG00000078415Danio rerio
 Lrrc3ENSMUSG00000051652Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
LRRC3B / Q96PB8 / leucine rich repeat containing 3BENSG0000017979647
A6NJW4 / LRRC3C / leucine rich repeat containing 3CENSG0000020491335
LRRC17 / Q8N6Y2 / leucine rich repeat containing 17ENSG0000012860623


Protein motifs (from Interpro)
Interpro ID Name
 IPR000372  Leucine-rich repeat N-terminal domain
 IPR001611  Leucine-rich repeat
 IPR003591  Leucine-rich repeat, typical subtype
 IPR032675  Leucine-rich repeat domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006469 negative regulation of protein kinase activity IBA
 biological_processGO:0019221 cytokine-mediated signaling pathway IBA
 biological_processGO:0046426 negative regulation of JAK-STAT cascade IBA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004860 protein kinase inhibitor activity IBA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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