ENSG00000160570


Homo sapiens

Features
Gene ID: ENSG00000160570
  
Biological name :DEDD2
  
Synonyms : death effector domain containing 2 / DEDD2 / Q8WXF8
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: -1
Band: q13.2
Gene start: 42198598
Gene end: 42220140
  
Corresponding Affymetrix probe sets: 225434_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000469233
Ensembl peptide - ENSP00000470082
Ensembl peptide - ENSP00000471512
Ensembl peptide - ENSP00000336972
Ensembl peptide - ENSP00000469898
NCBI entrez gene - 162989     See in Manteia.
OMIM - 617078
RefSeq - XM_017026403
RefSeq - NM_001270615
RefSeq - NM_133328
RefSeq - XM_011526569
RefSeq - XM_011526571
RefSeq - XM_011526572
RefSeq - XM_017026402
RefSeq - NM_001270614
RefSeq Peptide - NP_579874
RefSeq Peptide - NP_001257543
RefSeq Peptide - NP_001257544
swissprot - M0QYK9
swissprot - Q8WXF8
swissprot - M0QXK7
Ensembl - ENSG00000160570
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 dedd1ENSDARG00000002758Danio rerio
 Dedd2ENSMUSG00000054499Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
DEDD / O75618 / death effector domain containingENSG0000015879644


Protein motifs (from Interpro)
Interpro ID Name
 IPR001875  Death effector domain
 IPR011029  Death-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006396 RNA processing NAS
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0008625 extrinsic apoptotic signaling pathway via death domain receptors IMP
 biological_processGO:0016075 rRNA catabolic process NAS
 biological_processGO:0019725 cellular homeostasis NAS
 biological_processGO:0030262 apoptotic nuclear changes IDA
 biological_processGO:0035556 intracellular signal transduction NAS
 biological_processGO:0042981 regulation of apoptotic process IEA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated NAS
 biological_processGO:2001238 positive regulation of extrinsic apoptotic signaling pathway IMP
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005730 nucleolus IEA
 molecular_functionGO:0003677 DNA binding IBA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0030159 receptor signaling complex scaffold activity NAS


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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