ENSG00000160593


Homo sapiens

Features
Gene ID: ENSG00000160593
  
Biological name :JAML
  
Synonyms : JAML / junction adhesion molecule like / Q86YT9
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 11
Strand: -1
Band: q23.3
Gene start: 118193740
Gene end: 118225094
  
Corresponding Affymetrix probe sets: 228094_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000348635
Ensembl peptide - ENSP00000492467
Ensembl peptide - ENSP00000436117
Ensembl peptide - ENSP00000435145
Ensembl peptide - ENSP00000432769
Ensembl peptide - ENSP00000431791
Ensembl peptide - ENSP00000431614
Ensembl peptide - ENSP00000431218
Ensembl peptide - ENSP00000292067
NCBI entrez gene - 120425     See in Manteia.
OMIM - 609770
RefSeq - XM_017017215
RefSeq - NM_001098526
RefSeq - NM_001286570
RefSeq - NM_001286571
RefSeq - NM_153206
RefSeq - XM_005271407
RefSeq - XM_017017213
RefSeq - XM_017017214
RefSeq Peptide - NP_001273499
RefSeq Peptide - NP_001091996
RefSeq Peptide - NP_001273500
RefSeq Peptide - NP_694938
swissprot - E9PJJ4
swissprot - A0A1W2PRS4
swissprot - E9PNS8
swissprot - E9PKK2
swissprot - E9PR26
swissprot - E9PLF9
swissprot - Q86YT9
Ensembl - ENSG00000160593
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000044339Gallus gallus
 JamlENSMUSG00000048534Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000920  Myelin P0 protein-related
 IPR003599  Immunoglobulin subtype
 IPR007110  Immunoglobulin-like domain
 IPR013106  Immunoglobulin V-set domain
 IPR013783  Immunoglobulin-like fold
 IPR029871  Junctional adhesion molecule-like
 IPR036179  Immunoglobulin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002376 immune system process IEA
 biological_processGO:0007155 cell adhesion IEA
 biological_processGO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules IMP
 biological_processGO:0030593 neutrophil chemotaxis IMP
 biological_processGO:0035696 monocyte extravasation IMP
 biological_processGO:0046629 gamma-delta T cell activation ISS
 biological_processGO:0050776 regulation of immune response TAS
 biological_processGO:0050900 leukocyte migration TAS
 biological_processGO:0060054 positive regulation of epithelial cell proliferation involved in wound healing IEA
 biological_processGO:0072672 neutrophil extravasation IMP
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005923 bicellular tight junction IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030054 cell junction IEA
 molecular_functionGO:0005178 integrin binding IPI
 molecular_functionGO:0042803 protein homodimerization activity IDA
 molecular_functionGO:0050839 cell adhesion molecule binding IPI


Pathways (from Reactome)
Pathway description
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Cell surface interactions at the vascular wall


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000154639 CXADR / P78310 / CXADR, Ig-like cell adhesion molecule  / complex / reaction






 

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