ENSG00000160999


Homo sapiens

Features
Gene ID: ENSG00000160999
  
Biological name :SH2B2
  
Synonyms : SH2B2 / SH2B adaptor protein 2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 7
Strand: 1
Band: q22.1
Gene start: 102285091
Gene end: 102321711
  
Corresponding Affymetrix probe sets: 205367_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000401883
Ensembl peptide - ENSP00000483034
Ensembl peptide - ENSP00000440273
NCBI entrez gene - 10603     See in Manteia.
OMIM - 605300
RefSeq - XM_017011681
RefSeq - XM_005276975
RefSeq - XM_005276976
RefSeq - XM_005276977
RefSeq - XM_005276979
RefSeq - XM_011515740
RefSeq - XM_017011680
RefSeq - NM_001359229
RefSeq - NM_001359231
RefSeq - NM_020979
RefSeq Peptide - NP_001346160
RefSeq Peptide - NP_066189
RefSeq Peptide - NP_001346158
swissprot - C9JK89
swissprot - A0A0A0MTI2
swissprot - A0A087X016
Ensembl - ENSG00000160999
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 SH2B2ENSDARG00000090421Danio rerio
 SH2B2ENSGALG00000001828Gallus gallus
 Sh2b2ENSMUSG00000005057Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
SH2B1 / Q9NRF2 / SH2B adaptor protein 1ENSG0000017818837
SH2B3 / Q9UQQ2 / SH2B adaptor protein 3ENSG0000011125229


Protein motifs (from Interpro)
Interpro ID Name
 IPR000980  SH2 domain
 IPR001849  Pleckstrin homology domain
 IPR011993  PH-like domain superfamily
 IPR015012  Phenylalanine zipper
 IPR030520  SH2B adapter protein 2
 IPR030523  SH2B adapter protein
 IPR035058  SH2B2, SH2 domain
 IPR036290  Phenylalanine zipper superfamily
 IPR036860  SH2 domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0009967 positive regulation of signal transduction IEA
 biological_processGO:0035556 intracellular signal transduction IEA
 cellular_componentGO:0005829 cytosol IDA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0035591 signaling adaptor activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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