ENSG00000161048


Homo sapiens

Features
Gene ID: ENSG00000161048
  
Biological name :NAPEPLD
  
Synonyms : N-acyl phosphatidylethanolamine phospholipase D / NAPEPLD / Q6IQ20
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 7
Strand: -1
Band: q22.1
Gene start: 103099776
Gene end: 103149560
  
Corresponding Affymetrix probe sets: 226041_at (Human Genome U133 Plus 2.0 Array)   233539_at (Human Genome U133 Plus 2.0 Array)   238722_x_at (Human Genome U133 Plus 2.0 Array)   242229_at (Human Genome U133 Plus 2.0 Array)   242635_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000414778
Ensembl peptide - ENSP00000412376
Ensembl peptide - ENSP00000419188
Ensembl peptide - ENSP00000340093
Ensembl peptide - ENSP00000392775
Ensembl peptide - ENSP00000395138
Ensembl peptide - ENSP00000404391
Ensembl peptide - ENSP00000407112
NCBI entrez gene - 222236     See in Manteia.
OMIM - 612334
RefSeq - XM_017011855
RefSeq - XM_005250215
RefSeq - XM_005250218
RefSeq - XM_011515933
RefSeq - XM_011515934
RefSeq - XM_017011854
RefSeq - NM_001122838
RefSeq - NM_198990
RefSeq - XM_005250214
RefSeq Peptide - NP_001116310
RefSeq Peptide - NP_945341
swissprot - H0Y4Y2
swissprot - Q6IQ20
swissprot - C9JGB1
Ensembl - ENSG00000161048
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 napepldENSDARG00000009252Danio rerio
 NAPEPLDENSGALG00000008285Gallus gallus
 Q8BH82ENSMUSG00000044968Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001279  Metallo-beta-lactamase
 IPR024884  N-acyl-phosphatidylethanolamine-hydrolysing phospholipase D
 IPR036866  Ribonuclease Z/Hydroxyacylglutathione hydrolase-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001523 retinoid metabolic process TAS
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0006644 phospholipid metabolic process IEA
 biological_processGO:0007568 aging IEA
 biological_processGO:0009395 phospholipid catabolic process IEA
 biological_processGO:0016042 lipid catabolic process IEA
 biological_processGO:0035900 response to isolation stress IEA
 biological_processGO:0070291 N-acylethanolamine metabolic process IEA
 biological_processGO:1903999 negative regulation of eating behavior IEA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0042622 photoreceptor outer segment membrane TAS
 cellular_componentGO:0043227 membrane-bounded organelle IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0004620 phospholipase activity IEA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0042802 identical protein binding IPI
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity TAS
 molecular_functionGO:0102200 N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity IEA


Pathways (from Reactome)
Pathway description
Biosynthesis of A2E, implicated in retinal degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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