ENSMUSG00000044968


Mus musculus

Features
Gene ID: ENSMUSG00000044968
  
Biological name :Napepld
  
Synonyms : N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D / Napepld / Q8BH82
  
Possible biological names infered from orthology : N-acyl phosphatidylethanolamine phospholipase D / Q6IQ20
  
Species: Mus musculus
  
Chr. number: 5
Strand: -1
Band: A3
Gene start: 21662901
Gene end: 21701396
  
Corresponding Affymetrix probe sets: 10528332 (MoGene1.0st)   1437872_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000054458
Ensembl peptide - ENSMUSP00000110872
NCBI entrez gene - 242864     See in Manteia.
MGI - MGI:2140885
RefSeq - XM_006535712
RefSeq - NM_178728
RefSeq - XM_006535710
RefSeq - XM_006535711
RefSeq - XM_006535709
RefSeq Peptide - NP_848843
swissprot - Q8BH82
Ensembl - ENSMUSG00000044968
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 napepldENSDARG00000009252Danio rerio
 NAPEPLDENSGALG00000008285Gallus gallus
 Q6IQ20ENSG00000161048Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001279  Metallo-beta-lactamase
 IPR024884  N-acyl-phosphatidylethanolamine-hydrolysing phospholipase D
 IPR036866  Ribonuclease Z/Hydroxyacylglutathione hydrolase-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0006644 phospholipid metabolic process IEA
 biological_processGO:0007568 aging IEA
 biological_processGO:0009395 phospholipid catabolic process IEA
 biological_processGO:0016042 lipid catabolic process IEA
 biological_processGO:0035900 response to isolation stress IEA
 biological_processGO:0070291 N-acylethanolamine metabolic process IMP
 biological_processGO:1903999 negative regulation of eating behavior IEA
 cellular_componentGO:0005829 cytosol ISO
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0043227 membrane-bounded organelle IEA
 molecular_functionGO:0004620 phospholipase activity IEA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0042802 identical protein binding ISO
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity IMP
 molecular_functionGO:0102200 N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002118 abnormal lipid homeostasis "anomaly in the state of equilibrium in the body with respect to lipids in the fluids and tissues" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: S100a8tm1Hogg/S100a8tm1Hogg
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J * CD-1

 MP:0003633 abnormal nervous system physiology 
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Allelic Composition: Ctsbtm1Jde/Ctsbtm1Jde,Ctsktm1Psa/Ctsktm1Psa
Genetic Background: involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6J

 MP:0005584 abnormal enzyme/coenzyme activity "altered ability of any of these proteins, or their cofactors, to act as catalysts to induce chemical changes in other substances" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Gde1tm1Crv/Gde1tm1Crv,Napepldtm1Crv/Napepldtm1Crv
Genetic Background: involves: 129X1/SvJ * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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