ENSG00000161642


Homo sapiens

Features
Gene ID: ENSG00000161642
  
Biological name :ZNF385A
  
Synonyms : Q96PM9 / zinc finger protein 385A / ZNF385A
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 12
Strand: -1
Band: q13.13
Gene start: 54369133
Gene end: 54391298
  
Corresponding Affymetrix probe sets: 226111_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000450149
Ensembl peptide - ENSP00000449462
Ensembl peptide - ENSP00000450373
Ensembl peptide - ENSP00000293385
Ensembl peptide - ENSP00000338927
Ensembl peptide - ENSP00000377849
Ensembl peptide - ENSP00000446913
Ensembl peptide - ENSP00000447162
Ensembl peptide - ENSP00000448264
Ensembl peptide - ENSP00000448466
Ensembl peptide - ENSP00000448567
Ensembl peptide - ENSP00000448754
Ensembl peptide - ENSP00000449161
NCBI entrez gene - 25946     See in Manteia.
OMIM - 609124
RefSeq - XM_017019174
RefSeq - NM_001130967
RefSeq - NM_001130968
RefSeq - NM_001290001
RefSeq - NM_001290002
RefSeq - NM_001290004
RefSeq - NM_015481
RefSeq - XM_005268783
RefSeq - XM_006719342
RefSeq - XM_011538168
RefSeq - XM_011538169
RefSeq - XM_011538170
RefSeq - XM_011538171
RefSeq Peptide - NP_001124439
RefSeq Peptide - NP_001276930
RefSeq Peptide - NP_001276931
RefSeq Peptide - NP_001276933
RefSeq Peptide - NP_056296
RefSeq Peptide - NP_001124440
swissprot - H0YI55
swissprot - H0YIX3
swissprot - A0A024RB56
swissprot - Q96PM9
swissprot - F8VQ24
swissprot - F8VRY0
swissprot - F8VSJ1
swissprot - F8VWV6
swissprot - F8VY43
Ensembl - ENSG00000161642
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 znf385aENSDARG00000009899Danio rerio
 ENSGALG00000046448Gallus gallus
 Q8VD12ENSMUSG00000000552Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q569K4 / ZNF385B / zinc finger protein 385BENSG0000014433149
Q9H6B1 / ZNF385D / zinc finger protein 385DENSG0000015178948
ZNF385C / zinc finger protein 385CENSG0000018759542


Protein motifs (from Interpro)
Interpro ID Name
 IPR003604  Matrin/U1-C-like, C2H2-type zinc finger
 IPR013087  Zinc finger C2H2-type
 IPR026939  At2g23090-like
 IPR036236  Zinc finger C2H2 superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 biological_processGO:0006417 regulation of translation IEA
 biological_processGO:0006915 apoptotic process ISS
 biological_processGO:0006974 cellular response to DNA damage stimulus ISS
 biological_processGO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest TAS
 biological_processGO:0007599 hemostasis IEA
 biological_processGO:0007611 learning or memory IEA
 biological_processGO:0007626 locomotory behavior IEA
 biological_processGO:0008298 intracellular mRNA localization IEA
 biological_processGO:0010609 mRNA localization resulting in posttranscriptional regulation of gene expression IBA
 biological_processGO:0030220 platelet formation IEA
 biological_processGO:0035855 megakaryocyte development ISS
 biological_processGO:0045600 positive regulation of fat cell differentiation ISS
 biological_processGO:0070889 platelet alpha granule organization IEA
 biological_processGO:1901796 regulation of signal transduction by p53 class mediator TAS
 biological_processGO:1902164 positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator IMP
 biological_processGO:1902166 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator IMP
 biological_processGO:2000765 regulation of cytoplasmic translation IBA
 cellular_componentGO:0000790 nuclear chromatin IDA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005730 nucleolus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0030425 dendrite ISS
 cellular_componentGO:0042995 cell projection IEA
 cellular_componentGO:0043025 neuronal cell body ISS
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding NAS
 molecular_functionGO:0002039 p53 binding IPI
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0003730 mRNA 3"-UTR binding ISS
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest
TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest
Regulation of TP53 Activity through Association with Co-factors
Transcriptional activation of cell cycle inhibitor p21


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000141510 TP53 / P04637 / tumor protein p53  / complex / reaction






 

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contact: otassy@igbmc.fr