ENSG00000161940


Homo sapiens

Features
Gene ID: ENSG00000161940
  
Biological name :BCL6B
  
Synonyms : B cell CLL/lymphoma 6B / BCL6B / Q8N143
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 17
Strand: 1
Band: p13.1
Gene start: 7023020
Gene end: 7030290
  
Corresponding Affymetrix probe sets: 1554625_at (Human Genome U133 Plus 2.0 Array)   228311_at (Human Genome U133 Plus 2.0 Array)   242148_at (Human Genome U133 Plus 2.0 Array)   243825_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000293805
Ensembl peptide - ENSP00000460071
Ensembl peptide - ENSP00000460282
Ensembl peptide - ENSP00000445010
NCBI entrez gene - 255877     See in Manteia.
OMIM - 608992
RefSeq - NM_181844
RefSeq Peptide - NP_862827
swissprot - Q8N143
swissprot - H0YGW0
swissprot - I3L304
swissprot - I3L396
Ensembl - ENSG00000161940
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 bcl6bENSDARG00000069335Danio rerio
 Bcl6bENSMUSG00000000317Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
BCL6 / P41182 / B cell CLL/lymphoma 6ENSG0000011391652
Q8NCP5 / ZBTB44 / zinc finger and BTB domain containing 44ENSG0000019632327


Protein motifs (from Interpro)
Interpro ID Name
 IPR000210  BTB/POZ domain
 IPR011333  SKP1/BTB/POZ domain superfamily
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR013087  Zinc finger C2H2-type
 IPR036236  Zinc finger C2H2 superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0042092 type 2 immune response IBA
 biological_processGO:0042127 regulation of cell proliferation IBA
 biological_processGO:0045595 regulation of cell differentiation IBA
 biological_processGO:0050727 regulation of inflammatory response IBA
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding IEA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding NAS
 molecular_functionGO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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