ENSG00000161980


Homo sapiens

Features
Gene ID: ENSG00000161980
  
Biological name :POLR3K
  
Synonyms : POLR3K / Q9Y2Y1 / RNA polymerase III subunit K
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 16
Strand: -1
Band: p13.3
Gene start: 46407
Gene end: 53628
  
Corresponding Affymetrix probe sets: 218866_s_at (Human Genome U133 Plus 2.0 Array)   222766_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000293860
NCBI entrez gene - 51728     See in Manteia.
OMIM - 606007
RefSeq - NM_016310
RefSeq Peptide - NP_057394
swissprot - Q9Y2Y1
Ensembl - ENSG00000161980
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 polr3kENSDARG00000037835Danio rerio
 POLR3KENSGALG00000017681Gallus gallus
 Polr3kENSMUSG00000038628Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001222  Zinc finger, TFIIS-type
 IPR001529  DNA-directed RNA polymerase, M/15kDa subunit
 IPR012164  DNA-directed RNA polymerase subunit/transcription factor S
 IPR019761  DNA-directed RNA polymerase M, 15kDa subunit, conserved site
 IPR034014  Pol III subunit C11, C-terminal zinc ribbon


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002376 immune system process IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006379 mRNA cleavage IEA
 biological_processGO:0006383 transcription by RNA polymerase III TAS
 biological_processGO:0006386 termination of RNA polymerase III transcription IBA
 biological_processGO:0032481 positive regulation of type I interferon production TAS
 biological_processGO:0045087 innate immune response IEA
 biological_processGO:0051607 defense response to virus IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005666 DNA-directed RNA polymerase III complex TAS
 cellular_componentGO:0005730 nucleolus IEA
 cellular_componentGO:0005829 cytosol TAS
 molecular_functionGO:0001056 RNA polymerase III activity IBA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003899 DNA-directed 5"-3" RNA polymerase activity TAS
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Cytosolic sensors of pathogen-associated DNA
RNA Polymerase III Chain Elongation
RNA Polymerase III Transcription Termination
RNA Polymerase III Abortive And Retractive Initiation
RNA Polymerase III Transcription Initiation From Type 1 Promoter
RNA Polymerase III Transcription Initiation From Type 2 Promoter
RNA Polymerase III Transcription Initiation From Type 3 Promoter


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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