ENSG00000162191


Homo sapiens

Features
Gene ID: ENSG00000162191
  
Biological name :UBXN1
  
Synonyms : Q04323 / UBX domain protein 1 / UBXN1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 11
Strand: -1
Band: q12.3
Gene start: 62676498
Gene end: 62679117
  
Corresponding Affymetrix probe sets: 201871_s_at (Human Genome U133 Plus 2.0 Array)   210623_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000294119
Ensembl peptide - ENSP00000478250
Ensembl peptide - ENSP00000435964
Ensembl peptide - ENSP00000435625
Ensembl peptide - ENSP00000432189
Ensembl peptide - ENSP00000303991
NCBI entrez gene - 51035     See in Manteia.
OMIM - 616378
RefSeq - XM_017017874
RefSeq - NM_001286077
RefSeq - NM_001286078
RefSeq - NM_015853
RefSeq - XM_005274033
RefSeq - XM_011545090
RefSeq Peptide - NP_001273006
RefSeq Peptide - NP_001273007
RefSeq Peptide - NP_056937
swissprot - E9PJ81
swissprot - A0A087WTZ5
swissprot - A0A024R598
swissprot - A0A024R539
swissprot - E9PRQ7
swissprot - Q04323
swissprot - E9PS08
Ensembl - ENSG00000162191
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ubxn1ENSDARG00000090309Danio rerio
 Ubxn1ENSMUSG00000071655Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
UBXN4 / Q92575 / UBX domain protein 4ENSG0000014422422


Protein motifs (from Interpro)
Interpro ID Name
 IPR001012  UBX domain
 IPR009060  UBA-like superfamily
 IPR015940  Ubiquitin-associated domain
 IPR029071  Ubiquitin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006457 protein folding TAS
 biological_processGO:0031397 negative regulation of protein ubiquitination IDA
 biological_processGO:0032435 negative regulation of proteasomal ubiquitin-dependent protein catabolic process IDA
 biological_processGO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process NAS
 biological_processGO:1903094 negative regulation of protein K48-linked deubiquitination IDA
 biological_processGO:1904293 negative regulation of ERAD pathway IMP
 biological_processGO:2000157 negative regulation of ubiquitin-specific protease activity IDA
 cellular_componentGO:0000502 proteasome complex IDA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005783 endoplasmic reticulum IDA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0030425 dendrite IEA
 cellular_componentGO:0034098 VCP-NPL4-UFD1 AAA ATPase complex IDA
 cellular_componentGO:0043025 neuronal cell body IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0031593 polyubiquitin modification-dependent protein binding IDA
 molecular_functionGO:0031625 ubiquitin protein ligase binding IDA
 molecular_functionGO:0036435 K48-linked polyubiquitin modification-dependent protein binding IDA
 molecular_functionGO:0043130 ubiquitin binding IDA
 molecular_functionGO:0051117 ATPase binding IPI
 molecular_functionGO:0071796 K6-linked polyubiquitin modification-dependent protein binding IDA


Pathways (from Reactome)
Pathway description
N-glycan trimming in the ER and Calnexin/Calreticulin cycle


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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