ENSG00000162702


Homo sapiens

Features
Gene ID: ENSG00000162702
  
Biological name :ZNF281
  
Synonyms : Q9Y2X9 / zinc finger protein 281 / ZNF281
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: -1
Band: q32.1
Gene start: 200404940
Gene end: 200410056
  
Corresponding Affymetrix probe sets: 218401_s_at (Human Genome U133 Plus 2.0 Array)   222619_at (Human Genome U133 Plus 2.0 Array)   228785_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000294740
Ensembl peptide - ENSP00000356321
Ensembl peptide - ENSP00000356322
NCBI entrez gene - 23528     See in Manteia.
RefSeq - XM_017000888
RefSeq - NM_001281293
RefSeq - NM_001281294
RefSeq - NM_012482
RefSeq - XM_017000887
RefSeq Peptide - NP_036614
RefSeq Peptide - NP_001268222
RefSeq Peptide - NP_001268223
swissprot - Q9Y2X9
Ensembl - ENSG00000162702
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 znf281aENSDARG00000000567Danio rerio
 znf281bENSDARG00000035910Danio rerio
 ZNF281ENSGALG00000017376Gallus gallus
 Q99LI5ENSMUSG00000041483Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q9UQR1 / ZNF148 / zinc finger protein 148ENSG0000016384827
Q8NDX6 / ZNF740 / zinc finger protein 740ENSG000001396518
Q7Z7K2 / ZNF467 / zinc finger protein 467ENSG000001814448


Protein motifs (from Interpro)
Interpro ID Name
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR013087  Zinc finger C2H2-type
 IPR036236  Zinc finger C2H2 superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IDA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0010172 embryonic body morphogenesis ISS
 biological_processGO:0010629 negative regulation of gene expression IMP
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IMP
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IDA
 biological_processGO:0048863 stem cell differentiation ISS
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IDA
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IDA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding NAS
 molecular_functionGO:0001047 core promoter binding ISS
 molecular_functionGO:0001078 transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding IDA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IDA
 molecular_functionGO:0003714 transcription corepressor activity ISS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0043565 sequence-specific DNA binding IDA
 molecular_functionGO:0044212 transcription regulatory region DNA binding IDA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

1 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr