ENSG00000162851


Homo sapiens

Features
Gene ID: ENSG00000162851
  
Biological name :TFB2M
  
Synonyms : Q9H5Q4 / TFB2M / transcription factor B2, mitochondrial
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: -1
Band: q44
Gene start: 246540560
Gene end: 246566324
  
Corresponding Affymetrix probe sets: 1566930_at (Human Genome U133 Plus 2.0 Array)   1566931_at (Human Genome U133 Plus 2.0 Array)   1566932_x_at (Human Genome U133 Plus 2.0 Array)   218605_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000355471
NCBI entrez gene - 64216     See in Manteia.
OMIM - 607055
RefSeq - XM_017002055
RefSeq - NM_022366
RefSeq - XM_011544248
RefSeq Peptide - NP_071761
swissprot - Q9H5Q4
Ensembl - ENSG00000162851
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tfb2mENSDARG00000074756Danio rerio
 ENSGALG00000010651Gallus gallus
 Tfb2mENSMUSG00000026492Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001737  Ribosomal RNA adenine methyltransferase KsgA/Erm
 IPR016861  Mitochondrial transcription factor TFB2
 IPR020598  Ribosomal RNA adenine methylase transferase, N-terminal
 IPR029063  S-adenosyl-L-methionine-dependent methyltransferase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000154 rRNA modification IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006364 rRNA processing IEA
 biological_processGO:0006390 mitochondrial transcription IDA
 biological_processGO:0006391 transcription initiation from mitochondrial promoter IDA
 biological_processGO:0007005 mitochondrion organization TAS
 biological_processGO:0031167 rRNA methylation IEA
 biological_processGO:0032259 methylation IEA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IDA
 cellular_componentGO:0005739 mitochondrion IDA
 cellular_componentGO:0005759 mitochondrial matrix TAS
 cellular_componentGO:0042645 mitochondrial nucleoid IDA
 molecular_functionGO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity IBA
 molecular_functionGO:0003712 transcription coregulator activity IDA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0008168 methyltransferase activity IEA
 molecular_functionGO:0008649 rRNA methyltransferase activity IEA
 molecular_functionGO:0016740 transferase activity IEA


Pathways (from Reactome)
Pathway description
Mitochondrial transcription initiation
Transcriptional activation of mitochondrial biogenesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000108064 TFAM / Q00059 / transcription factor A, mitochondrial  / reaction / complex
 ENSG00000099821 O00411 / POLRMT / RNA polymerase mitochondrial  / complex






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr