ENSG00000162882


Homo sapiens

Features
Gene ID: ENSG00000162882
  
Biological name :HAAO
  
Synonyms : 3-hydroxyanthranilate 3,4-dioxygenase / HAAO / P46952
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 2
Strand: -1
Band: p21
Gene start: 42767089
Gene end: 42792593
  
Corresponding Affymetrix probe sets: 205657_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000412601
Ensembl peptide - ENSP00000294973
NCBI entrez gene - 23498     See in Manteia.
OMIM - 604521
RefSeq - XM_017003717
RefSeq - NM_012205
RefSeq - XM_011532729
RefSeq - XM_011532730
RefSeq - XM_011532731
RefSeq - XM_005264230
RefSeq Peptide - NP_036337
swissprot - P46952
swissprot - C9IY88
Ensembl - ENSG00000162882
  
Related genetic diseases (OMIM): 617660 - Vertebral, cardiac, renal, and limb defects syndrome 1, 617660
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 haaoENSDARG00000076487Danio rerio
 HAAOENSGALG00000009926Gallus gallus
 HaaoENSMUSG00000000673Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR010329  3-hydroxyanthranilic acid dioxygenase
 IPR011051  RmlC-like cupin domain superfamily
 IPR014710  RmlC-like jelly roll fold
 IPR016700  3-hydroxyanthranilate 3, 4-dioxygenase, metazoan


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006569 tryptophan catabolic process TAS
 biological_processGO:0009435 NAD biosynthetic process IMP
 biological_processGO:0010043 response to zinc ion IDA
 biological_processGO:0019363 pyridine nucleotide biosynthetic process IEA
 biological_processGO:0019805 quinolinate biosynthetic process NAS
 biological_processGO:0022900 electron transport chain IEA
 biological_processGO:0046686 response to cadmium ion IDA
 biological_processGO:0055114 oxidation-reduction process IEA
 biological_processGO:0070050 neuron cellular homeostasis IMP
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0000334 3-hydroxyanthranilate 3,4-dioxygenase activity IEA
 molecular_functionGO:0005506 iron ion binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008198 ferrous iron binding IDA
 molecular_functionGO:0009055 electron transfer activity NAS
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0051213 dioxygenase activity IEA


Pathways (from Reactome)
Pathway description
Tryptophan catabolism


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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