ENSMUSG00000000673


Mus musculus

Features
Gene ID: ENSMUSG00000000673
  
Biological name :Haao
  
Synonyms : 3-hydroxyanthranilate 3,4-dioxygenase / Haao / Q78JT3
  
Possible biological names infered from orthology : P46952
  
Species: Mus musculus
  
Chr. number: 17
Strand: -1
Band: E4
Gene start: 83831356
Gene end: 83846790
  
Corresponding Affymetrix probe sets: 10453260 (MoGene1.0st)   1432492_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000000687
NCBI entrez gene - 107766     See in Manteia.
MGI - MGI:1349444
RefSeq - XM_006523467
RefSeq - NM_025325
RefSeq - XM_006523465
RefSeq - XM_006523466
RefSeq - XM_006523463
RefSeq Peptide - NP_079601
swissprot - Q78JT3
Ensembl - ENSMUSG00000000673
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 haaoENSDARG00000076487Danio rerio
 HAAOENSGALG00000009926Gallus gallus
 HAAOENSG00000162882Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR010329  3-hydroxyanthranilic acid dioxygenase
 IPR011051  RmlC-like cupin domain superfamily
 IPR014710  RmlC-like jelly roll fold
 IPR016700  3-hydroxyanthranilate 3, 4-dioxygenase, metazoan


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0009435 NAD biosynthetic process ISS
 biological_processGO:0010043 response to zinc ion IEA
 biological_processGO:0019363 pyridine nucleotide biosynthetic process IEA
 biological_processGO:0019805 quinolinate biosynthetic process IEA
 biological_processGO:0046686 response to cadmium ion IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 biological_processGO:0070050 neuron cellular homeostasis IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 molecular_functionGO:0000334 3-hydroxyanthranilate 3,4-dioxygenase activity ISO
 molecular_functionGO:0005506 iron ion binding IEA
 molecular_functionGO:0008198 ferrous iron binding IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0051213 dioxygenase activity IEA


Pathways (from Reactome)
Pathway description
Tryptophan catabolism


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001415 increased exploration in new environment "greater amount of time spent investigating new location" [J:28825]
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Allelic Composition: Phc1tm1Os/Phc1tm1Os,Tg(Myh7-Phc1)#Yota/0
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0003360 depression-related behavior 
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Allelic Composition: Phc1tm1Os/Phc1tm1Os,Tg(Myh7-Phc1)#Yota/0
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0013242 abnormal amino acid metabolism "any anomaly in the chemical reactions and pathways involving an amino acid, including metabolic, catabolic and biosynthetic processes" [MPD:Molly]
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Allelic Composition: Phc1tm1Os/Phc1tm1Os,Tg(Myh7-Phc1)#Yota/0
Genetic Background: involves: 129S2/SvPas * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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