ENSG00000163975


Homo sapiens

Features
Gene ID: ENSG00000163975
  
Biological name :MELTF
  
Synonyms : melanotransferrin / MELTF / P08582
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 3
Strand: -1
Band: q29
Gene start: 196988621
Gene end: 197029816
  
Corresponding Affymetrix probe sets: 1556538_at (Human Genome U133 Plus 2.0 Array)   220043_s_at (Human Genome U133 Plus 2.0 Array)   223723_at (Human Genome U133 Plus 2.0 Array)   235911_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000393439
Ensembl peptide - ENSP00000296350
Ensembl peptide - ENSP00000296351
NCBI entrez gene - 4241     See in Manteia.
OMIM - 155750
RefSeq - XM_011512851
RefSeq - NM_005929
RefSeq - NM_033316
RefSeq - XM_006713643
RefSeq - XM_011512850
RefSeq Peptide - NP_005920
RefSeq Peptide - NP_201573
swissprot - P08582
swissprot - Q53XS6
swissprot - C9JVN1
Ensembl - ENSG00000163975
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 meltfENSDARG00000075159Danio rerio
 MELTFENSGALG00000006855Gallus gallus
 MeltfENSMUSG00000022780Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
TF / P02787 / transferrinENSG0000009151339
LTF / P02788 / lactotransferrinENSG0000001222339


Protein motifs (from Interpro)
Interpro ID Name
 IPR001156  Transferrin-like domain
 IPR016357  Transferrin
 IPR018195  Transferrin family, iron binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006501 C-terminal protein lipidation TAS
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0010756 positive regulation of plasminogen activation IDA
 biological_processGO:0043687 post-translational protein modification TAS
 biological_processGO:0044267 cellular protein metabolic process TAS
 biological_processGO:0055072 iron ion homeostasis IEA
 biological_processGO:0090091 positive regulation of extracellular matrix disassembly IDA
 biological_processGO:0097286 iron ion import IMP
 biological_processGO:1900025 negative regulation of substrate adhesion-dependent cell spreading IDA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IEA
 cellular_componentGO:0005788 endoplasmic reticulum lumen TAS
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane TAS
 cellular_componentGO:0009986 cell surface IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0031225 anchored component of membrane IEA
 cellular_componentGO:0046658 anchored component of plasma membrane IDA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0005506 iron ion binding TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Post-translational modification: synthesis of GPI-anchored proteins
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
Post-translational protein phosphorylation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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