ENSG00000164024


Homo sapiens

Features
Gene ID: ENSG00000164024
  
Biological name :METAP1
  
Synonyms : METAP1 / methionyl aminopeptidase 1 / P53582
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 4
Strand: 1
Band: q23
Gene start: 98995620
Gene end: 99062813
  
Corresponding Affymetrix probe sets: 212673_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000427563
Ensembl peptide - ENSP00000427187
Ensembl peptide - ENSP00000485924
Ensembl peptide - ENSP00000296411
Ensembl peptide - ENSP00000422689
Ensembl peptide - ENSP00000423071
Ensembl peptide - ENSP00000424462
Ensembl peptide - ENSP00000426702
NCBI entrez gene - 23173     See in Manteia.
OMIM - 610151
RefSeq - XM_017007917
RefSeq - NM_015143
RefSeq - XM_011531777
RefSeq - XM_011531778
RefSeq - XM_011531779
RefSeq - XM_017007914
RefSeq - XM_017007915
RefSeq - XM_017007916
RefSeq Peptide - NP_055958
swissprot - H0Y955
swissprot - H0Y9L0
swissprot - H0Y903
swissprot - D6RF24
swissprot - P53582
swissprot - H0YAI3
Ensembl - ENSG00000164024
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 metap1ENSDARG00000033440Danio rerio
 METAP1ENSGALG00000012239Gallus gallus
 Metap1ENSMUSG00000005813Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q6UB28 / METAP1D / methionyl aminopeptidase type 1D, mitochondrialENSG0000017287835


Protein motifs (from Interpro)
Interpro ID Name
 IPR000994  Peptidase M24
 IPR001714  Peptidase M24, methionine aminopeptidase
 IPR002467  Peptidase M24A, methionine aminopeptidase, subfamily 1
 IPR031615  MYND-like zinc finger, mRNA-binding
 IPR036005  Creatinase/aminopeptidase-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006417 regulation of translation TAS
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0018206 peptidyl-methionine modification TAS
 biological_processGO:0022400 regulation of rhodopsin mediated signaling pathway TAS
 biological_processGO:0031365 N-terminal protein amino acid modification TAS
 biological_processGO:0070527 platelet aggregation HMP
 cellular_componentGO:0005737 cytoplasm TAS
 cellular_componentGO:0005829 cytosol TAS
 molecular_functionGO:0004177 aminopeptidase activity IEA
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008235 metalloexopeptidase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Inactivation, recovery and regulation of the phototransduction cascade


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000114349 GNAT1 / P11488 / G protein subunit alpha transducin 1  / reaction






 

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