ENSG00000164270


Homo sapiens

Features
Gene ID: ENSG00000164270
  
Biological name :HTR4
  
Synonyms : 5-hydroxytryptamine receptor 4 / HTR4 / Q13639
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 5
Strand: -1
Band: q32
Gene start: 148451032
Gene end: 148677235
  
Corresponding Affymetrix probe sets: 207577_at (Human Genome U133 Plus 2.0 Array)   207578_s_at (Human Genome U133 Plus 2.0 Array)   216939_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000430874
Ensembl peptide - ENSP00000485747
Ensembl peptide - ENSP00000435904
Ensembl peptide - ENSP00000430979
Ensembl peptide - ENSP00000353915
Ensembl peptide - ENSP00000355037
Ensembl peptide - ENSP00000367120
Ensembl peptide - ENSP00000427913
Ensembl peptide - ENSP00000428320
Ensembl peptide - ENSP00000429634
Ensembl peptide - ENSP00000430451
NCBI entrez gene - 3360     See in Manteia.
OMIM - 602164
RefSeq - NM_199453
RefSeq - NM_001286410
RefSeq - NM_001040169
RefSeq - NM_001040172
RefSeq - NM_001040173
RefSeq - NM_000870
RefSeq Peptide - NP_001035263
RefSeq Peptide - NP_955525
RefSeq Peptide - NP_000861
RefSeq Peptide - NP_001035259
RefSeq Peptide - NP_001035262
RefSeq Peptide - NP_001273339
swissprot - Q13639
swissprot - E5RHV8
swissprot - E5RK45
Ensembl - ENSG00000164270
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 htr4ENSDARG00000061940Danio rerio
 HTR4ENSGALG00000001383Gallus gallus
 Htr4ENSMUSG00000026322Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
TAAR1 / Q96RJ0 / trace amine associated receptor 1ENSG0000014639927
TAAR9 / Q96RI9 / trace amine associated receptor 9 (gene/pseudogene)ENSG0000023711025
TAAR2 / Q9P1P5 / trace amine associated receptor 2 (gene/pseudogene)ENSG0000014637825
TAAR8 / Q969N4 / trace amine associated receptor 8ENSG0000014638525
TAAR6 / Q96RI8 / trace amine associated receptor 6ENSG0000014638324
TAAR5 / O14804 / trace amine associated receptor 5ENSG0000013556923


Protein motifs (from Interpro)
Interpro ID Name
 IPR000276  G protein-coupled receptor, rhodopsin-like
 IPR001520  5-Hydroxytryptamine 4 receptor
 IPR017452  GPCR, rhodopsin-like, 7TM


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway TAS
 biological_processGO:0007187 G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger TAS
 biological_processGO:0007214 gamma-aminobutyric acid signaling pathway IBA
 biological_processGO:0007268 chemical synaptic transmission IEA
 biological_processGO:0032098 regulation of appetite IEA
 biological_processGO:0098664 G-protein coupled serotonin receptor signaling pathway IEA
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005768 endosome IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane TAS
 cellular_componentGO:0016020 membrane IDA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IEA
 molecular_functionGO:0004993 G-protein coupled serotonin receptor activity IDA
 molecular_functionGO:0042802 identical protein binding IPI


Pathways (from Reactome)
Pathway description
Serotonin receptors
G alpha (s) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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