ENSG00000164695


Homo sapiens

Features
Gene ID: ENSG00000164695
  
Biological name :CHMP4C
  
Synonyms : charged multivesicular body protein 4C / CHMP4C / Q96CF2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 8
Strand: 1
Band: q21.13
Gene start: 81732434
Gene end: 81759515
  
Corresponding Affymetrix probe sets: 226803_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000297265
NCBI entrez gene - 92421     See in Manteia.
OMIM - 610899
RefSeq - NM_152284
RefSeq Peptide - NP_689497
swissprot - Q96CF2
Ensembl - ENSG00000164695
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 chmp4cENSDARG00000007418Danio rerio
 CHMP4CENSGALG00000043573Gallus gallus
 Chmp4cENSMUSG00000027536Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CHMP4B / Q9H444 / charged multivesicular body protein 4BENSG0000010142162
CHMP4A / Q9BY43 / charged multivesicular body protein 4AENSG0000025450554


Protein motifs (from Interpro)
Interpro ID Name
 IPR005024  Snf7 family


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000920 cell separation after cytokinesis IMP
 biological_processGO:0006997 nucleus organization IMP
 biological_processGO:0007034 vacuolar transport IEA
 biological_processGO:0007080 mitotic metaphase plate congression IMP
 biological_processGO:0009838 abscission IMP
 biological_processGO:0010824 regulation of centrosome duplication IMP
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0016197 endosomal transport TAS
 biological_processGO:0016236 macroautophagy TAS
 biological_processGO:0019058 viral life cycle TAS
 biological_processGO:0032466 negative regulation of cytokinesis IMP
 biological_processGO:0036258 multivesicular body assembly TAS
 biological_processGO:0039702 viral budding via host ESCRT complex TAS
 biological_processGO:0044878 mitotic cytokinesis checkpoint IMP
 biological_processGO:0050792 regulation of viral process IMP
 biological_processGO:0090611 ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway IMP
 biological_processGO:1901673 regulation of mitotic spindle assembly IMP
 biological_processGO:1902188 positive regulation of viral release from host cell IMP
 cellular_componentGO:0000815 ESCRT III complex TAS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005768 endosome IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030496 midbody IDA
 cellular_componentGO:0031902 late endosome membrane IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 cellular_componentGO:0090543 Flemming body IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0042803 protein homodimerization activity IPI


Pathways (from Reactome)
Pathway description
Budding and maturation of HIV virion
Macroautophagy
Endosomal Sorting Complex Required For Transport (ESCRT)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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