ENSG00000254505


Homo sapiens

Features
Gene ID: ENSG00000254505
  
Biological name :CHMP4A
  
Synonyms : charged multivesicular body protein 4A / CHMP4A / Q9BY43
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 14
Strand: -1
Band: q12
Gene start: 24209583
Gene end: 24213869
  
Corresponding Affymetrix probe sets: 218571_s_at (Human Genome U133 Plus 2.0 Array)   218572_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000436224
Ensembl peptide - ENSP00000476412
Ensembl peptide - ENSP00000449757
Ensembl peptide - ENSP00000448869
Ensembl peptide - ENSP00000324205
Ensembl peptide - ENSP00000432575
NCBI entrez gene - 29082     See in Manteia.
OMIM - 610051
RefSeq - NM_014169
RefSeq Peptide - NP_054888
swissprot - H0YIN6
swissprot - E9PQI5
swissprot - Q9BY43
swissprot - E9PQ80
swissprot - H0YI89
Ensembl - ENSG00000254505
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
No match


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CHMP4B / Q9H444 / charged multivesicular body protein 4BENSG0000010142152
CHMP4C / Q96CF2 / charged multivesicular body protein 4CENSG0000016469547


Protein motifs (from Interpro)
Interpro ID Name
 IPR005024  Snf7 family


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000920 cell separation after cytokinesis IMP
 biological_processGO:0006620 posttranslational protein targeting to endoplasmic reticulum membrane IMP
 biological_processGO:0006900 vesicle budding from membrane IMP
 biological_processGO:0006997 nucleus organization IMP
 biological_processGO:0007034 vacuolar transport IEA
 biological_processGO:0007080 mitotic metaphase plate congression IMP
 biological_processGO:0010324 membrane invagination IMP
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0016197 endosomal transport TAS
 biological_processGO:0016236 macroautophagy TAS
 biological_processGO:0019058 viral life cycle TAS
 biological_processGO:0036258 multivesicular body assembly TAS
 biological_processGO:0039702 viral budding via host ESCRT complex IGI
 biological_processGO:0051258 protein polymerization IMP
 biological_processGO:0051260 protein homooligomerization IMP
 biological_processGO:0097320 plasma membrane tubulation IMP
 biological_processGO:1901215 negative regulation of neuron death IMP
 biological_processGO:1902902 negative regulation of autophagosome assembly IMP
 cellular_componentGO:0000815 ESCRT III complex IDA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005768 endosome IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005886 plasma membrane IDA
 cellular_componentGO:0009898 cytoplasmic side of plasma membrane IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030117 membrane coat IMP
 cellular_componentGO:0030496 midbody IDA
 cellular_componentGO:0030659 cytoplasmic vesicle membrane IEA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 cellular_componentGO:0031902 late endosome membrane IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008289 lipid binding IEA
 molecular_functionGO:0042802 identical protein binding IMP
 molecular_functionGO:0042803 protein homodimerization activity IPI
 molecular_functionGO:0051117 ATPase binding IPI


Pathways (from Reactome)
Pathway description
Budding and maturation of HIV virion
Macroautophagy
Endosomal Sorting Complex Required For Transport (ESCRT)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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