ENSG00000164715


Homo sapiens

Features
Gene ID: ENSG00000164715
  
Biological name :LMTK2
  
Synonyms : lemur tyrosine kinase 2 / LMTK2 / Q8IWU2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 7
Strand: 1
Band: q21.3
Gene start: 98106885
Gene end: 98209633
  
Corresponding Affymetrix probe sets: 206223_at (Human Genome U133 Plus 2.0 Array)   226375_at (Human Genome U133 Plus 2.0 Array)   235307_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000297293
NCBI entrez gene - 22853     See in Manteia.
OMIM - 610989
RefSeq - NM_014916
RefSeq - XM_011515981
RefSeq Peptide - NP_055731
swissprot - Q8IWU2
Ensembl - ENSG00000164715
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 lmtk2ENSDARG00000076324Danio rerio
 si:dkey-40m6.8ENSDARG00000029114Danio rerio
 LMTK2ENSGALG00000003479Gallus gallus
 Lmtk2ENSMUSG00000038970Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
AATK / Q6ZMQ8 / apoptosis associated tyrosine kinaseENSG0000018140929
LMTK3 / Q96Q04 / lemur tyrosine kinase 3ENSG0000014223525


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR001245  Serine-threonine/tyrosine-protein kinase, catalytic domain
 IPR008266  Tyrosine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR017441  Protein kinase, ATP binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001881 receptor recycling IMP
 biological_processGO:0006468 protein phosphorylation IDA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0018105 peptidyl-serine phosphorylation IDA
 biological_processGO:0018107 peptidyl-threonine phosphorylation IDA
 biological_processGO:0032456 endocytic recycling IMP
 biological_processGO:0032515 negative regulation of phosphoprotein phosphatase activity IEA
 biological_processGO:0033572 transferrin transport IMP
 biological_processGO:0045022 early endosome to late endosome transport IMP
 biological_processGO:0046777 protein autophosphorylation IDA
 cellular_componentGO:0005769 early endosome IDA
 cellular_componentGO:0005794 Golgi apparatus IDA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030426 growth cone IEA
 cellular_componentGO:0043025 neuronal cell body IEA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IDA
 cellular_componentGO:0055037 recycling endosome IDA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IEA
 molecular_functionGO:0004864 protein phosphatase inhibitor activity IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding NAS
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0070853 myosin VI binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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