ENSG00000165457


Homo sapiens

Features
Gene ID: ENSG00000165457
  
Biological name :FOLR2
  
Synonyms : folate receptor beta / FOLR2 / P14207
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 11
Strand: 1
Band: q13.4
Gene start: 72216601
Gene end: 72221950
  
Corresponding Affymetrix probe sets: 204829_s_at (Human Genome U133 Plus 2.0 Array)   229619_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000443307
Ensembl peptide - ENSP00000441547
Ensembl peptide - ENSP00000444794
Ensembl peptide - ENSP00000480592
Ensembl peptide - ENSP00000298223
Ensembl peptide - ENSP00000321957
Ensembl peptide - ENSP00000405638
Ensembl peptide - ENSP00000414094
Ensembl peptide - ENSP00000438568
Ensembl peptide - ENSP00000440337
NCBI entrez gene - 2350     See in Manteia.
OMIM - 136425
RefSeq - XM_005273856
RefSeq - NM_000803
RefSeq - NM_001113534
RefSeq - NM_001113535
RefSeq - NM_001113536
RefSeq Peptide - NP_001107007
RefSeq Peptide - NP_001107008
RefSeq Peptide - NP_000794
RefSeq Peptide - NP_001107006
swissprot - P14207
swissprot - A0A087WWY2
swissprot - E7EU04
swissprot - F5GXV3
swissprot - F5GZ45
swissprot - F5H4Z6
swissprot - F5H3Z4
swissprot - F5H5L8
swissprot - J3KQP4
swissprot - J3KR13
Ensembl - ENSG00000165457
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 IZUMO1RENSDARG00000102442Danio rerio
 FOLR1ENSGALG00000017343Gallus gallus
 Folr2ENSMUSG00000032725Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
FOLR3 / P41439 / folate receptor 3ENSG0000011020374
FOLR1 / P15328 / folate receptor 1ENSG0000011019571
A6ND01 / IZUMO1R / IZUMO1 receptor, JUNOENSG0000018356053


Protein motifs (from Interpro)
Interpro ID Name
 IPR004269  Folate receptor
 IPR018143  Folate receptor-like
 IPR032937  Folate receptor beta


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006501 C-terminal protein lipidation TAS
 biological_processGO:0006898 receptor-mediated endocytosis IC
 biological_processGO:0006954 inflammatory response NAS
 biological_processGO:0008284 positive regulation of cell proliferation IMP
 biological_processGO:0015884 folic acid transport IEA
 biological_processGO:0046655 folic acid metabolic process TAS
 biological_processGO:0050758 regulation of thymidylate synthase biosynthetic process IC
 biological_processGO:0071231 cellular response to folic acid IEA
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0009986 cell surface IDA
 cellular_componentGO:0016020 membrane TAS
 cellular_componentGO:0031225 anchored component of membrane IEA
 cellular_componentGO:0031362 anchored component of external side of plasma membrane IDA
 molecular_functionGO:0005542 folic acid binding IEA
 molecular_functionGO:0008144 drug binding IPI
 molecular_functionGO:0008517 folic acid transmembrane transporter activity IEA
 molecular_functionGO:0051870 methotrexate binding IDA
 molecular_functionGO:0061714 folic acid receptor activity IDA


Pathways (from Reactome)
Pathway description
Post-translational modification: synthesis of GPI-anchored proteins
Metabolism of folate and pterines


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr