ENSMUSG00000032725


Mus musculus

Features
Gene ID: ENSMUSG00000032725
  
Biological name :Folr2
  
Synonyms : Folate receptor beta / Folr2 / Q05685
  
Possible biological names infered from orthology : P14207
  
Species: Mus musculus
  
Chr. number: 7
Strand: -1
Band: E2
Gene start: 101839988
Gene end: 101857194
  
Corresponding Affymetrix probe sets: 10566026 (MoGene1.0st)   1451648_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000148085
Ensembl peptide - ENSMUSP00000091692
Ensembl peptide - ENSMUSP00000147283
Ensembl peptide - ENSMUSP00000147920
NCBI entrez gene - 14276     See in Manteia.
MGI - MGI:95569
RefSeq - XM_006507371
RefSeq - NM_001303231
RefSeq - NM_001303239
RefSeq - NM_008035
RefSeq Peptide - NP_001290160
RefSeq Peptide - NP_001290168
RefSeq Peptide - NP_032061
swissprot - A0A1B0GQW7
swissprot - A0A1B0GSV4
swissprot - Q05685
Ensembl - ENSMUSG00000032725
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 IZUMO1RENSDARG00000102442Danio rerio
 FOLR1ENSGALG00000017343Gallus gallus
 FOLR2ENSG00000165457Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Folr1 / P35846 / Folate receptor alpha / P15328* / folate receptor 1*ENSMUSG0000000182769
Q9EQF4 / Izumo1r / IZUMO1 receptor, JUNO / A6ND01*ENSMUSG0000003193345


Protein motifs (from Interpro)
Interpro ID Name
 IPR004269  Folate receptor
 IPR018143  Folate receptor-like
 IPR032937  Folate receptor beta


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006620 posttranslational protein targeting to endoplasmic reticulum membrane TAS
 biological_processGO:0008284 positive regulation of cell proliferation IEA
 biological_processGO:0015884 folic acid transport IEA
 biological_processGO:0071231 cellular response to folic acid IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0009986 cell surface IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0031225 anchored component of membrane IEA
 cellular_componentGO:0031362 anchored component of external side of plasma membrane IEA
 molecular_functionGO:0005542 folic acid binding IEA
 molecular_functionGO:0008144 drug binding IEA
 molecular_functionGO:0008517 folic acid transmembrane transporter activity IEA
 molecular_functionGO:0051870 methotrexate binding IEA
 molecular_functionGO:0061714 folic acid receptor activity IEA


Pathways (from Reactome)
Pathway description
Post-translational modification: synthesis of GPI-anchored proteins
Metabolism of folate and pterines


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Ptprcloc/Ptprcloc
Genetic Background: C57BL/6JSfdAnu-Ptprcloc/AnuApb

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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