ENSMUSG00000031933


Mus musculus

Features
Gene ID: ENSMUSG00000031933
  
Biological name :Izumo1r
  
Synonyms : Izumo1r / IZUMO1 receptor, JUNO / Q9EQF4
  
Possible biological names infered from orthology : A6ND01
  
Species: Mus musculus
  
Chr. number: 9
Strand: -1
Band: A2
Gene start: 14885814
Gene end: 14903949
  
Corresponding Affymetrix probe sets: 10590974 (MoGene1.0st)   1420700_s_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000034409
Ensembl peptide - ENSMUSP00000113387
Ensembl peptide - ENSMUSP00000113459
Ensembl peptide - ENSMUSP00000118680
Ensembl peptide - ENSMUSP00000063632
NCBI entrez gene - 64931     See in Manteia.
MGI - MGI:1929185
RefSeq - XM_017313504
RefSeq - XM_006510530
RefSeq - XM_006510531
RefSeq - XM_006510533
RefSeq - XM_006510536
RefSeq - XM_017313501
RefSeq - XM_017313502
RefSeq - XM_017313503
RefSeq - NM_022888
RefSeq - NM_176807
RefSeq Peptide - NP_789777
RefSeq Peptide - NP_075026
swissprot - Q9EQF4
swissprot - G5E8D3
swissprot - Q8BY83
swissprot - D3YZI1
swissprot - D3Z631
Ensembl - ENSMUSG00000031933
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 IZUMO1RENSDARG00000102442Danio rerio
 FOLR1ENSGALG00000017343Gallus gallus
 A6ND01ENSG00000183560Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Folr2 / Q05685 / Folate receptor beta / P14207*ENSMUSG0000003272547
Folr1 / P35846 / Folate receptor alpha / P15328* / folate receptor 1*ENSMUSG0000000182746


Protein motifs (from Interpro)
Interpro ID Name
 IPR004269  Folate receptor
 IPR018143  Folate receptor-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007155 cell adhesion IMP
 biological_processGO:0007338 single fertilization IMP
 biological_processGO:0007342 fusion of sperm to egg plasma membrane involved in single fertilization IMP
 biological_processGO:0035036 sperm-egg recognition IMP
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane TAS
 cellular_componentGO:0031225 anchored component of membrane IEA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
Post-translational modification: synthesis of GPI-anchored proteins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000242 impaired fertilization "defect or reduced ability in the process beginning with penetration of the secondary oocyte by the spermatozoon and completed by fusion of the male and female pronucei" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Izumo1rtm1a(KOMP)Wtsi/Izumo1rtm1a(KOMP)Wtsi
Genetic Background: involves: C57BL/6N * C57BL/6NTac

 MP:0001926 female infertility "inability of female to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:34193]
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Allelic Composition: Smarcb1tm1Sho/Smarcb1+
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J * DBA/2J

Allelic Composition: Izumo1rtm2a(KOMP)Wtsi/Izumo1rtm2a(KOMP)Wtsi
Genetic Background: C57BL/6N-Izumo1rtm2a(KOMP)Wtsi/Wtsi

Allelic Composition: Izumo1rtm1b(KOMP)Wtsi/Izumo1rtm1b(KOMP)Wtsi
Genetic Background: C57BL/6N-Izumo1rtm1b(KOMP)Wtsi/Rbrc

Allelic Composition: Izumo1rtm1a(KOMP)Wtsi/Izumo1rtm1a(KOMP)Wtsi
Genetic Background: involves: C57BL/6N * C57BL/6NTac

Allelic Composition: Izumo1rtm2a(KOMP)Wtsi/Izumo1rtm2a(KOMP)Wtsi
Genetic Background: involves: C57BL/6N

 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Nrxn1tm5Sud/Nrxn1tm5Sud
Genetic Background: involves: C57BL/6

 MP:0003019 increased circulating chloride level "elevated concentration of chlorine salts in the circulation" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, RGD:Rat Genome Database submission]
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Allelic Composition: Izumo1rtm2a(KOMP)Wtsi/Izumo1rtm2a(KOMP)Wtsi
Genetic Background: C57BL/6N-Izumo1rtm2a(KOMP)Wtsi/Wtsi

 MP:0003960 increased lean body mass "more than average fat-free physical bulk or volume of the body including all its components except adipose tissue" [honda:Hiraoki Onda, Mouse GEnome Informatics Curator]
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Allelic Composition: Izumo1rtm2a(KOMP)Wtsi/Izumo1rtm2a(KOMP)Wtsi
Genetic Background: C57BL/6N-Izumo1rtm2a(KOMP)Wtsi/Wtsi

 MP:0005560 decreased circulating glucose level "less than the normal concentration in the blood of this major monosaccharide of the body; it is an important energy source" [RGD:Rat Genome Database submission, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Izumo1rtm2a(KOMP)Wtsi/Izumo1rtm2a(KOMP)Wtsi
Genetic Background: C57BL/6N-Izumo1rtm2a(KOMP)Wtsi/Wtsi

 MP:0008805 decreased circulating amylase level "reduction in the concentration of a group of amylolytic enzymes that cleave starch, glycogen, and related alpha-1,4-glucans in the blood" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MESH:D08.811.277.450.066, MGI:brs "Beverly Richards-Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Izumo1rtm2a(KOMP)Wtsi/Izumo1rtm2a(KOMP)Wtsi
Genetic Background: C57BL/6N-Izumo1rtm2a(KOMP)Wtsi/Wtsi

 MP:0010025 decreased total body fat amount "less than the normal total amount of connective tissue composed of fat cells within the entire body" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Izumo1rtm2a(KOMP)Wtsi/Izumo1rtm2a(KOMP)Wtsi
Genetic Background: C57BL/6N-Izumo1rtm2a(KOMP)Wtsi/Wtsi

 MP:0010088 decreased circulating fructosamine level "decrease in the concentration in the blood of total non enzymatic glycated proteins in the blood" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Izumo1rtm2a(KOMP)Wtsi/Izumo1rtm2a(KOMP)Wtsi
Genetic Background: C57BL/6N-Izumo1rtm2a(KOMP)Wtsi/Wtsi

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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