ENSG00000165609


Homo sapiens

Features
Gene ID: ENSG00000165609
  
Biological name :NUDT5
  
Synonyms : nudix hydrolase 5 / NUDT5 / Q9UKK9
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 10
Strand: -1
Band: p14
Gene start: 12165325
Gene end: 12196144
  
Corresponding Affymetrix probe sets: 222824_at (Human Genome U133 Plus 2.0 Array)   223100_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000368219
Ensembl peptide - ENSP00000445116
Ensembl peptide - ENSP00000436844
Ensembl peptide - ENSP00000419628
Ensembl peptide - ENSP00000407856
Ensembl peptide - ENSP00000368222
Ensembl peptide - ENSP00000368209
NCBI entrez gene - 11164     See in Manteia.
OMIM - 609230
RefSeq - NM_014142
RefSeq - NM_001321647
RefSeq - NM_001321648
RefSeq Peptide - NP_001308577
RefSeq Peptide - NP_001308576
RefSeq Peptide - NP_054861
swissprot - Q9UKK9
swissprot - A6NJU6
swissprot - A6NFX8
swissprot - A6NCQ0
swissprot - H0YEY4
swissprot - C9JYY9
Ensembl - ENSG00000165609
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 nudt5ENSDARG00000078073Danio rerio
 NUDT5ENSGALG00000013967Gallus gallus
 Nudt5ENSMUSG00000025817Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000086  NUDIX hydrolase domain
 IPR015797  NUDIX hydrolase-like domain superfamily
 IPR020084  NUDIX hydrolase, conserved site
 IPR020476  NUDIX hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006139 nucleobase-containing compound metabolic process IEA
 biological_processGO:0006338 chromatin remodeling IDA
 biological_processGO:0009117 nucleotide metabolic process NAS
 biological_processGO:0009191 ribonucleoside diphosphate catabolic process IDA
 biological_processGO:0019303 D-ribose catabolic process NAS
 biological_processGO:0034656 nucleobase-containing small molecule catabolic process TAS
 biological_processGO:1990966 ATP generation from poly-ADP-D-ribose IDA
 cellular_componentGO:0005622 intracellular NAS
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0000287 magnesium ion binding IDA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016779 nucleotidyltransferase activity IDA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0017110 nucleoside-diphosphatase activity IEA
 molecular_functionGO:0019144 ADP-sugar diphosphatase activity IDA
 molecular_functionGO:0030515 snoRNA binding ISS
 molecular_functionGO:0042803 protein homodimerization activity IDA
 molecular_functionGO:0044715 8-oxo-dGDP phosphatase activity IDA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0047631 ADP-ribose diphosphatase activity EXP


Pathways (from Reactome)
Pathway description
Phosphate bond hydrolysis by NUDT proteins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000165609 NUDT5 / Q9UKK9 / nudix hydrolase 5  / complex






 

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