ENSG00000165905


Homo sapiens

Features
Gene ID: ENSG00000165905
  
Biological name :LARGE2
  
Synonyms : LARGE2 / LARGE xylosyl- and glucuronyltransferase 2 / Q8N3Y3
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 11
Strand: 1
Band: p11.2
Gene start: 45921621
Gene end: 45929096
  
Corresponding Affymetrix probe sets: 227829_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000433328
Ensembl peptide - ENSP00000432869
Ensembl peptide - ENSP00000434325
Ensembl peptide - ENSP00000324570
Ensembl peptide - ENSP00000385235
Ensembl peptide - ENSP00000431932
NCBI entrez gene - 120071     See in Manteia.
OMIM - 609709
RefSeq - XM_017017173
RefSeq - XM_011519886
RefSeq - XM_011519888
RefSeq - XM_011519889
RefSeq - XM_011519890
RefSeq - XM_011519891
RefSeq - XM_011519892
RefSeq - XM_011519893
RefSeq - NM_001300721
RefSeq - NM_001300722
RefSeq - NM_152312
RefSeq - XM_005252787
RefSeq - XM_006718140
RefSeq - XM_006718141
RefSeq Peptide - NP_689525
RefSeq Peptide - NP_001287650
RefSeq Peptide - NP_001287651
swissprot - E9PIZ2
swissprot - Q8N3Y3
swissprot - H0YDU6
swissprot - H0YDB8
Ensembl - ENSG00000165905
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 LARGE2ENSGALG00000008418Gallus gallus
 Large2ENSMUSG00000040434Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
LARGE1 / O95461 / LARGE xylosyl- and glucuronyltransferase 1ENSG0000013342463
B4GAT1 / O43505 / beta-1,4-glucuronyltransferase 1ENSG0000017468413
Q8NBI6 / XXYLT1 / xyloside xylosyltransferase 1ENSG0000017395011


Protein motifs (from Interpro)
Interpro ID Name
 IPR002495  Glycosyl transferase, family 8
 IPR029044  Nucleotide-diphospho-sugar transferases


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006486 protein glycosylation IEA
 biological_processGO:0006493 protein O-linked glycosylation TAS
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0035269 protein O-linked mannosylation IDA
 biological_processGO:0046716 muscle cell cellular homeostasis ISS
 cellular_componentGO:0000139 Golgi membrane TAS
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0015020 glucuronosyltransferase activity TAS
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016757 transferase activity, transferring glycosyl groups IEA
 molecular_functionGO:0030145 manganese ion binding TAS
 molecular_functionGO:0035252 UDP-xylosyltransferase activity TAS
 molecular_functionGO:0042285 xylosyltransferase activity ISS
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
O-linked glycosylation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000174684 B4GAT1 / O43505 / beta-1,4-glucuronyltransferase 1  / complex






 

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