ENSG00000166164


Homo sapiens

Features
Gene ID: ENSG00000166164
  
Biological name :BRD7
  
Synonyms : BRD7 / bromodomain containing 7 / Q9NPI1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 16
Strand: -1
Band: q12.1
Gene start: 50313487
Gene end: 50368934
  
Corresponding Affymetrix probe sets: 221776_s_at (Human Genome U133 Plus 2.0 Array)   222737_s_at (Human Genome U133 Plus 2.0 Array)   228289_at (Human Genome U133 Plus 2.0 Array)   238545_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000378180
Ensembl peptide - ENSP00000378181
Ensembl peptide - ENSP00000458430
Ensembl peptide - ENSP00000461556
NCBI entrez gene - 29117     See in Manteia.
RefSeq - XM_017023181
RefSeq - XM_011523048
RefSeq - XM_011523049
RefSeq - XM_011523050
RefSeq - XM_017023179
RefSeq - XM_017023180
RefSeq - NM_001173984
RefSeq - NM_013263
RefSeq - XM_011523046
RefSeq - XM_011523047
RefSeq Peptide - NP_001167455
RefSeq Peptide - NP_037395
swissprot - I3L4V5
swissprot - Q9NPI1
swissprot - I3L0Y7
Ensembl - ENSG00000166164
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 brd7ENSDARG00000008380Danio rerio
 BRD7ENSGALG00000003786Gallus gallus
 Brd7ENSMUSG00000031660Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
BRD9 / Q9H8M2 / bromodomain containing 9ENSG0000002831031


Protein motifs (from Interpro)
Interpro ID Name
 IPR001487  Bromodomain
 IPR021900  Protein of unknown function DUF3512
 IPR036427  Bromodomain-like superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IDA
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0008285 negative regulation of cell proliferation IDA
 biological_processGO:0016055 Wnt signaling pathway IEA
 biological_processGO:0035066 positive regulation of histone acetylation IDA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IDA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IDA
 biological_processGO:1901796 regulation of signal transduction by p53 class mediator TAS
 biological_processGO:2000134 negative regulation of G1/S transition of mitotic cell cycle IDA
 cellular_componentGO:0005634 nucleus TAS
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005737 cytoplasm TAS
 cellular_componentGO:0005829 cytosol IDA
 molecular_functionGO:0002039 p53 binding IPI
 molecular_functionGO:0003713 transcription coactivator activity IDA
 molecular_functionGO:0003714 transcription corepressor activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008134 transcription factor binding IDA
 molecular_functionGO:0042393 histone binding IDA
 molecular_functionGO:0044212 transcription regulatory region DNA binding IDA
 molecular_functionGO:0070577 lysine-acetylated histone binding IDA


Pathways (from Reactome)
Pathway description
Regulation of TP53 Activity through Acetylation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000100393 EP300 / Q09472 / E1A binding protein p300  / complex / reaction
 ENSG00000141510 TP53 / P04637 / tumor protein p53  / complex / reaction






 

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