ENSG00000167136


Homo sapiens

Features
Gene ID: ENSG00000167136
  
Biological name :ENDOG
  
Synonyms : ENDOG / endonuclease G / Q14249
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 9
Strand: 1
Band: q34.11
Gene start: 128818474
Gene end: 128822677
  
Corresponding Affymetrix probe sets: 204824_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000361725
NCBI entrez gene - 2021     See in Manteia.
OMIM - 600440
RefSeq - XM_011518347
RefSeq - NM_004435
RefSeq Peptide - NP_004426
swissprot - Q14249
swissprot - E5KNL5
Ensembl - ENSG00000167136
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 endogENSDARG00000058865Danio rerio
 ENDOGENSGALG00000026221Gallus gallus
 EndogENSMUSG00000015337Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
EXOG / Q9Y2C4 / exo/endonuclease GENSG0000015703633


Protein motifs (from Interpro)
Interpro ID Name
 IPR001604  DNA/RNA non-specific endonuclease
 IPR018524  DNA/RNA non-specific endonuclease, active site
 IPR020821  Extracellular Endonuclease, subunit A


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001701 in utero embryonic development IEA
 biological_processGO:0006309 apoptotic DNA fragmentation IBA
 biological_processGO:0006310 DNA recombination TAS
 biological_processGO:0007568 aging IEA
 biological_processGO:0009612 response to mechanical stimulus IEA
 biological_processGO:0032355 response to estradiol IEA
 biological_processGO:0034599 cellular response to oxidative stress IEA
 biological_processGO:0034612 response to tumor necrosis factor IEA
 biological_processGO:0036475 neuron death in response to oxidative stress IEA
 biological_processGO:0043065 positive regulation of apoptotic process IEA
 biological_processGO:0046677 response to antibiotic IEA
 biological_processGO:0071277 cellular response to calcium ion IEA
 biological_processGO:0071333 cellular response to glucose stimulus IEA
 biological_processGO:0071456 cellular response to hypoxia IEA
 biological_processGO:1901300 positive regulation of hydrogen peroxide-mediated programmed cell death IEA
 biological_processGO:1902512 positive regulation of apoptotic DNA fragmentation IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0043204 perikaryon IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0004518 nuclease activity IEA
 molecular_functionGO:0004519 endonuclease activity IEA
 molecular_functionGO:0004536 deoxyribonuclease activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr