ENSG00000167191


Homo sapiens

Features
Gene ID: ENSG00000167191
  
Biological name :GPRC5B
  
Synonyms : GPRC5B / G protein-coupled receptor class C group 5 member B / Q9NZH0
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 16
Strand: -1
Band: p12.3
Gene start: 19856691
Gene end: 19886167
  
Corresponding Affymetrix probe sets: 203631_s_at (Human Genome U133 Plus 2.0 Array)   203632_s_at (Human Genome U133 Plus 2.0 Array)   225511_at (Human Genome U133 Plus 2.0 Array)   228313_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000457080
Ensembl peptide - ENSP00000457018
Ensembl peptide - ENSP00000457283
Ensembl peptide - ENSP00000300571
Ensembl peptide - ENSP00000442858
Ensembl peptide - ENSP00000454667
Ensembl peptide - ENSP00000454727
Ensembl peptide - ENSP00000455960
Ensembl peptide - ENSP00000456724
NCBI entrez gene - 51704     See in Manteia.
OMIM - 605948
RefSeq - XM_006721052
RefSeq - NM_001304771
RefSeq - NM_016235
RefSeq - XM_006721051
RefSeq Peptide - NP_057319
RefSeq Peptide - NP_001291700
swissprot - Q9NZH0
swissprot - A0A024QYX2
swissprot - H3BN33
swissprot - H3BQV9
swissprot - H3BT47
swissprot - H3BSJ1
swissprot - H3BT93
Ensembl - ENSG00000167191
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 gprc5baENSDARG00000077080Danio rerio
 gprc5bbENSDARG00000075141Danio rerio
 GPRC5BENSGALG00000002028Gallus gallus
 Gprc5bENSMUSG00000008734Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
GPRC5C / Q9NQ84 / G protein-coupled receptor class C group 5 member CENSG0000017041239
GPRC5A / Q8NFJ5 / G protein-coupled receptor class C group 5 member AENSG0000001358829
GPRC5D / Q9NZD1 / G protein-coupled receptor class C group 5 member DENSG0000011129127


Protein motifs (from Interpro)
Interpro ID Name
 IPR017978  GPCR family 3, C-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IEA
 biological_processGO:0032147 activation of protein kinase activity IEA
 biological_processGO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling ISS
 biological_processGO:0045666 positive regulation of neuron differentiation ISS
 biological_processGO:0050729 positive regulation of inflammatory response ISS
 biological_processGO:0060907 positive regulation of macrophage cytokine production ISS
 biological_processGO:0061098 positive regulation of protein tyrosine kinase activity ISS
 biological_processGO:0090263 positive regulation of canonical Wnt signaling pathway ISS
 cellular_componentGO:0005615 extracellular space HDA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005730 nucleolus IDA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0009986 cell surface ISS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030659 cytoplasmic vesicle membrane IEA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IDA
 cellular_componentGO:0070062 extracellular exosome IDA
 molecular_functionGO:0001664 G-protein coupled receptor binding ISS
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IEA
 molecular_functionGO:0019901 protein kinase binding ISS
 molecular_functionGO:0030295 protein kinase activator activity IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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