ENSG00000167967


Homo sapiens

Features
Gene ID: ENSG00000167967
  
Biological name :E4F1
  
Synonyms : E4F1 / E4F transcription factor 1 / Q66K89
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 16
Strand: 1
Band: p13.3
Gene start: 2223566
Gene end: 2235742
  
Corresponding Affymetrix probe sets: 218524_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000454652
Ensembl peptide - ENSP00000456760
Ensembl peptide - ENSP00000457672
Ensembl peptide - ENSP00000301727
Ensembl peptide - ENSP00000456005
NCBI entrez gene - 1877     See in Manteia.
OMIM - 603022
RefSeq - XM_017023011
RefSeq - NM_001288778
RefSeq - NM_004424
RefSeq - XM_005255155
RefSeq - XM_005255156
RefSeq - XM_006720858
RefSeq - XM_011522402
RefSeq - XM_011522403
RefSeq - XM_017023010
RefSeq - NM_001288776
RefSeq Peptide - NP_004415
RefSeq Peptide - NP_001275705
RefSeq Peptide - NP_001275707
swissprot - H3BQZ4
swissprot - H3BN24
swissprot - Q66K89
swissprot - H3BSL4
swissprot - H3BUJ7
Ensembl - ENSG00000167967
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 e4f1ENSDARG00000038243Danio rerio
 E4F1ENSGALG00000005900Gallus gallus
 E4f1ENSMUSG00000024137Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR013087  Zinc finger C2H2-type
 IPR036236  Zinc finger C2H2 superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IDA
 biological_processGO:0006260 DNA replication IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0008283 cell proliferation TAS
 biological_processGO:0009794 regulation of mitotic cell cycle, embryonic IEA
 biological_processGO:0010564 regulation of cell cycle process IEA
 biological_processGO:0016032 viral process IEA
 biological_processGO:0016567 protein ubiquitination IEA
 biological_processGO:0040008 regulation of growth IEA
 biological_processGO:0051301 cell division IEA
 biological_processGO:0071850 mitotic cell cycle arrest TAS
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005819 spindle IEA
 molecular_functionGO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding IDA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding NAS
 molecular_functionGO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding IC
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003677 DNA binding TAS
 molecular_functionGO:0003700 DNA-binding transcription factor activity TAS
 molecular_functionGO:0003713 transcription coactivator activity TAS
 molecular_functionGO:0003714 transcription corepressor activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0035497 cAMP response element binding IDA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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