ENSG00000168078


Homo sapiens

Features
Gene ID: ENSG00000168078
  
Biological name :PBK
  
Synonyms : PBK / PDZ binding kinase / Q96KB5
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 8
Strand: -1
Band: p21.1
Gene start: 27809620
Gene end: 27838095
  
Corresponding Affymetrix probe sets: 219148_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000301905
Ensembl peptide - ENSP00000428489
Ensembl peptide - ENSP00000428438
Ensembl peptide - ENSP00000427892
NCBI entrez gene - 55872     See in Manteia.
OMIM - 611210
RefSeq - NM_018492
RefSeq - XM_006716368
RefSeq - NM_001278945
RefSeq Peptide - NP_001265874
RefSeq Peptide - NP_060962
swissprot - E5RFX4
swissprot - Q96KB5
swissprot - V9HWH0
swissprot - E5RIE1
Ensembl - ENSG00000168078
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 pbkENSDARG00000007221Danio rerio
 PBKENSGALG00000016582Gallus gallus
 PbkENSMUSG00000022033Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR034368  Lymphokine-activated killer T-cell-originated protein kinase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000278 mitotic cell cycle IEA
 biological_processGO:0001933 negative regulation of protein phosphorylation IEA
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0032435 negative regulation of proteasomal ubiquitin-dependent protein catabolic process IEA
 biological_processGO:0032873 negative regulation of stress-activated MAPK cascade IEA
 biological_processGO:0034644 cellular response to UV IEA
 biological_processGO:0050728 negative regulation of inflammatory response IEA
 cellular_componentGO:0005634 nucleus IDA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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