ENSG00000168393


Homo sapiens

Features
Gene ID: ENSG00000168393
  
Biological name :DTYMK
  
Synonyms : deoxythymidylate kinase / DTYMK / P23919
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 2
Strand: -1
Band: q37.3
Gene start: 241675742
Gene end: 241686991
  
Corresponding Affymetrix probe sets: 1553983_at (Human Genome U133 Plus 2.0 Array)   1553984_s_at (Human Genome U133 Plus 2.0 Array)   1565693_at (Human Genome U133 Plus 2.0 Array)   1565694_at (Human Genome U133 Plus 2.0 Array)   203270_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000383581
Ensembl peptide - ENSP00000408939
Ensembl peptide - ENSP00000410647
Ensembl peptide - ENSP00000304802
Ensembl peptide - ENSP00000387379
NCBI entrez gene - 1841     See in Manteia.
OMIM - 188345
RefSeq - NM_001320902
RefSeq - NM_001165031
RefSeq - NM_001320903
RefSeq - NM_001320904
RefSeq - NM_001320905
RefSeq - NM_012145
RefSeq Peptide - NP_001307834
RefSeq Peptide - NP_036277
RefSeq Peptide - NP_001158503
RefSeq Peptide - NP_001307831
RefSeq Peptide - NP_001307832
RefSeq Peptide - NP_001307833
swissprot - G5E9E9
swissprot - H7BZ20
swissprot - P23919
swissprot - Q6FGU2
swissprot - H7C312
swissprot - H7C3A4
Ensembl - ENSG00000168393
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 dtymkENSDARG00000052103Danio rerio
 DTYMKENSGALG00000006305Gallus gallus
 DtymkENSMUSG00000026281Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR018094  Thymidylate kinase
 IPR018095  Thymidylate kinase, conserved site
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006227 dUDP biosynthetic process IBA
 biological_processGO:0006233 dTDP biosynthetic process IEA
 biological_processGO:0006235 dTTP biosynthetic process IBA
 biological_processGO:0008283 cell proliferation TAS
 biological_processGO:0009165 nucleotide biosynthetic process IEA
 biological_processGO:0015949 nucleobase-containing small molecule interconversion TAS
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0043627 response to estrogen IEA
 biological_processGO:0045445 myoblast differentiation IEA
 biological_processGO:0046686 response to cadmium ion IEA
 biological_processGO:0046939 nucleotide phosphorylation IEA
 biological_processGO:0046940 nucleoside monophosphate phosphorylation IEA
 biological_processGO:0071363 cellular response to growth factor stimulus IEA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005758 mitochondrial intermembrane space IEA
 cellular_componentGO:0005759 mitochondrial matrix IEA
 cellular_componentGO:0005829 cytosol TAS
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004798 thymidylate kinase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0009041 uridylate kinase activity IBA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0050145 nucleoside monophosphate kinase activity EXP


Pathways (from Reactome)
Pathway description
Interconversion of nucleotide di- and triphosphates


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000168393 DTYMK / P23919 / deoxythymidylate kinase  / complex






 

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