ENSG00000168412


Homo sapiens

Features
Gene ID: ENSG00000168412
  
Biological name :MTNR1A
  
Synonyms : melatonin receptor 1A / MTNR1A / P48039
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 4
Strand: -1
Band: q35.2
Gene start: 186533655
Gene end: 186555567
  
Corresponding Affymetrix probe sets: 221369_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000302811
NCBI entrez gene - 4543     See in Manteia.
OMIM - 600665
RefSeq - NM_005958
RefSeq Peptide - NP_005949
swissprot - P48039
Ensembl - ENSG00000168412
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 MTNR1AENSGALG00000013576Gallus gallus
 Mtnr1aENSMUSG00000054764Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
MTNR1B / P49286 / melatonin receptor 1BENSG0000013464057
GPR50 / Q13585 / G protein-coupled receptor 50ENSG0000010219546
GPR135 / Q8IZ08 / G protein-coupled receptor 135ENSG0000018161921
AC018709.1ENSG0000027229716


Protein motifs (from Interpro)
Interpro ID Name
 IPR000025  Melatonin receptor family
 IPR000276  G protein-coupled receptor, rhodopsin-like
 IPR002278  Melatonin receptor 1A/1B
 IPR017452  GPCR, rhodopsin-like, 7TM
 IPR027459  Melatonin receptor 1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway TAS
 biological_processGO:0007187 G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger TAS
 biological_processGO:0007617 mating behavior TAS
 biological_processGO:0007623 circadian rhythm TAS
 biological_processGO:0030828 obsolete positive regulation of cGMP biosynthetic process IDA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0043235 receptor complex IDA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008502 melatonin receptor activity TAS
 molecular_functionGO:0042562 hormone binding IPI
 molecular_functionGO:0097159 organic cyclic compound binding IPI


Pathways (from Reactome)
Pathway description
Class A/1 (Rhodopsin-like receptors)
G alpha (i) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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