ENSG00000168502


Homo sapiens

Features
Gene ID: ENSG00000168502
  
Biological name :MTCL1
  
Synonyms : microtubule crosslinking factor 1 / MTCL1 / Q9Y4B5
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 18
Strand: 1
Band: p11.22
Gene start: 8705661
Gene end: 8832778
  
Corresponding Affymetrix probe sets: 213358_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000463506
Ensembl peptide - ENSP00000463438
Ensembl peptide - ENSP00000463465
Ensembl peptide - ENSP00000305027
Ensembl peptide - ENSP00000352927
Ensembl peptide - ENSP00000382924
Ensembl peptide - ENSP00000429556
NCBI entrez gene - 23255     See in Manteia.
OMIM - 615766
RefSeq - XM_017025675
RefSeq - XM_017025671
RefSeq - XM_017025672
RefSeq - XM_017025673
RefSeq - XM_017025674
RefSeq - NM_015210
RefSeq - XM_005258098
RefSeq - XM_005258099
RefSeq - XM_011525640
RefSeq - XM_011525641
RefSeq Peptide - NP_056025
swissprot - J3QLE1
swissprot - J3QL92
swissprot - Q9Y4B5
Ensembl - ENSG00000168502
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 mtcl1ENSDARG00000091408Danio rerio
 MTCL1ENSGALG00000038316Gallus gallus
 Mtcl1ENSMUSG00000052105Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
SOGA1 / O94964 / suppressor of glucose, autophagy associated 1ENSG0000014963936
Q5TF21 / AL096711.2 / Protein SOGA3 ENSG0000025533020
SOGA3 / Q5TF21 / SOGA family member 3ENSG0000021433820


Protein motifs (from Interpro)
Interpro ID Name
 IPR027881  Protein SOGA
 IPR027882  Domain of unknown function DUF4482


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001578 microtubule bundle formation IBA
 biological_processGO:0010506 regulation of autophagy IEA
 biological_processGO:0045197 establishment or maintenance of epithelial cell apical/basal polarity IBA
 biological_processGO:0090314 positive regulation of protein targeting to membrane ISS
 biological_processGO:2000576 positive regulation of microtubule motor activity ISS
 cellular_componentGO:0000922 spindle pole IEA
 cellular_componentGO:0005615 extracellular space IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016324 apical plasma membrane IEA
 cellular_componentGO:0016327 apicolateral plasma membrane IBA
 cellular_componentGO:0016328 lateral plasma membrane IBA
 cellular_componentGO:0030496 midbody IEA
 cellular_componentGO:0097427 microtubule bundle IBA
 molecular_functionGO:0003723 RNA binding HDA
 molecular_functionGO:0008017 microtubule binding IDA
 molecular_functionGO:0042803 protein homodimerization activity ISS


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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