ENSG00000168826


Homo sapiens

Features
Gene ID: ENSG00000168826
  
Biological name :ZBTB49
  
Synonyms : Q6ZSB9 / ZBTB49 / zinc finger and BTB domain containing 49
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 4
Strand: 1
Band: p16.3
Gene start: 4290251
Gene end: 4321786
  
Corresponding Affymetrix probe sets: 229089_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000421654
Ensembl peptide - ENSP00000426765
Ensembl peptide - ENSP00000425747
Ensembl peptide - ENSP00000424525
Ensembl peptide - ENSP00000422321
Ensembl peptide - ENSP00000338807
NCBI entrez gene - 166793     See in Manteia.
OMIM - 616238
RefSeq - XM_017007835
RefSeq - NM_001330625
RefSeq - NM_145291
RefSeq - XM_005247951
RefSeq - XM_006713864
RefSeq Peptide - NP_001317554
RefSeq Peptide - NP_660334
swissprot - D6RB16
swissprot - D6RC96
swissprot - H0Y8P2
swissprot - Q6ZSB9
swissprot - H0YAD4
swissprot - D6RJ00
Ensembl - ENSG00000168826
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 zbtb49ENSDARG00000102111Danio rerio
 ZBTB49ENSGALG00000015009Gallus gallus
 Q8BXX2ENSMUSG00000029127Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
MYNN / Q9NPC7 / myoneurinENSG0000008527423
OVOL1 / O14753 / ovo like transcriptional repressor 1ENSG000001728188
OVOL2 / Q9BRP0 / ovo like zinc finger 2ENSG000001258508
OVOL3 / O00110 / ovo like zinc finger 3ENSG000001052616


Protein motifs (from Interpro)
Interpro ID Name
 IPR000210  BTB/POZ domain
 IPR011333  SKP1/BTB/POZ domain superfamily
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR013087  Zinc finger C2H2-type
 IPR036236  Zinc finger C2H2 superfamily
 IPR036792  Aspartate carbamoyltransferase regulatory subunit, C-terminal domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0007050 cell cycle arrest IDA
 biological_processGO:0008285 negative regulation of cell proliferation IDA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IDA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0015630 microtubule cytoskeleton IDA
 molecular_functionGO:0001223 transcription coactivator binding IPI
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0008134 transcription factor binding IPI
 molecular_functionGO:0043565 sequence-specific DNA binding IDA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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