ENSG00000169021


Homo sapiens

Features
Gene ID: ENSG00000169021
  
Biological name :UQCRFS1
  
Synonyms : P47985 / ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 / UQCRFS1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: -1
Band: q12
Gene start: 29205321
Gene end: 29213541
  
Corresponding Affymetrix probe sets: 208909_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000306397
NCBI entrez gene - 7386     See in Manteia.
OMIM - 191327
RefSeq - NM_006003
RefSeq Peptide - NP_005994
swissprot - P47985
Ensembl - ENSG00000169021
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 uqcrfs1ENSDARG00000007745Danio rerio
 Q5ZLR5ENSGALG00000025819Gallus gallus
 Q9CR68ENSMUSG00000038462Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR004192  Cytochrome b-c1 complex subunit Rieske, transmembrane domain
 IPR005805  Rieske iron-sulphur protein, C-terminal
 IPR006317  Ubiquinol-cytochrome c reductase, iron-sulphur subunit
 IPR011070  Globular protein, non-globular alpha/beta subunit
 IPR014349  Rieske iron-sulphur protein
 IPR015248  Ubiquinol-cytochrome c reductase 8kDa, N-terminal
 IPR017941  Rieske [2Fe-2S] iron-sulphur domain
 IPR036922  Rieske [2Fe-2S] iron-sulphur domain superfamily
 IPR037008  Cytochrome b-c1 complex subunit Rieske, transmembrane domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c TAS
 biological_processGO:0009725 response to hormone IEA
 biological_processGO:0042493 response to drug IEA
 biological_processGO:0046677 response to antibiotic IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005743 mitochondrial inner membrane TAS
 cellular_componentGO:0005750 mitochondrial respiratory chain complex III IEA
 cellular_componentGO:0005751 mitochondrial respiratory chain complex IV IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0031966 mitochondrial membrane IEA
 cellular_componentGO:0070469 respiratory chain IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008121 ubiquinol-cytochrome-c reductase activity IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0016679 oxidoreductase activity, acting on diphenols and related substances as donors IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0051536 iron-sulfur cluster binding IEA
 molecular_functionGO:0051537 2 iron, 2 sulfur cluster binding IEA


Pathways (from Reactome)
Pathway description
Respiratory electron transport


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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