ENSG00000169129


Homo sapiens

Features
Gene ID: ENSG00000169129
  
Biological name :AFAP1L2
  
Synonyms : actin filament associated protein 1 like 2 / AFAP1L2 / Q8N4X5
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 10
Strand: -1
Band: q25.3
Gene start: 114294824
Gene end: 114404756
  
Corresponding Affymetrix probe sets: 226829_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000303042
Ensembl peptide - ENSP00000358276
Ensembl peptide - ENSP00000396781
NCBI entrez gene - 84632     See in Manteia.
OMIM - 612420
RefSeq - NM_032550
RefSeq - XM_017016832
RefSeq - NM_001001936
RefSeq - NM_001287824
RefSeq - NM_001351069
RefSeq - NM_001351074
RefSeq - XM_017016825
RefSeq - XM_017016826
RefSeq - XM_017016827
RefSeq - XM_017016828
RefSeq - XM_017016829
RefSeq - XM_017016830
RefSeq - XM_017016831
RefSeq - XM_005270233
RefSeq - XM_005270237
RefSeq - XM_005270241
RefSeq - XM_005270242
RefSeq - XM_011540286
RefSeq - XM_011540289
RefSeq - XM_011540290
RefSeq - XM_017016792
RefSeq - XM_017016793
RefSeq - XM_017016794
RefSeq - XM_017016795
RefSeq - XM_017016796
RefSeq - XM_017016797
RefSeq - XM_017016798
RefSeq - XM_017016799
RefSeq - XM_017016800
RefSeq - XM_017016801
RefSeq - XM_017016802
RefSeq - XM_017016803
RefSeq - XM_017016804
RefSeq - XM_017016805
RefSeq - XM_017016806
RefSeq - XM_017016807
RefSeq - XM_017016808
RefSeq - XM_017016809
RefSeq - XM_017016810
RefSeq - XM_017016811
RefSeq - XM_017016812
RefSeq - XM_017016813
RefSeq - XM_017016814
RefSeq - XM_017016815
RefSeq - XM_017016816
RefSeq - XM_017016817
RefSeq - XM_017016818
RefSeq - XM_017016819
RefSeq - XM_017016820
RefSeq - XM_017016821
RefSeq - XM_017016822
RefSeq - XM_017016823
RefSeq - XM_017016824
RefSeq Peptide - NP_001001936
RefSeq Peptide - NP_001274753
RefSeq Peptide - NP_001337998
RefSeq Peptide - NP_001338003
RefSeq Peptide - NP_115939
swissprot - Q8N4X5
swissprot - F6QUH3
Ensembl - ENSG00000169129
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 afap1l2ENSDARG00000074806Danio rerio
 AFAP1L2ENSGALG00000008999Gallus gallus
 Q5DTU0ENSMUSG00000025083Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
AFAP1 / Q8N556 / actin filament associated protein 1ENSG0000019652633
Q8TED9 / AFAP1L1 / actin filament associated protein 1 like 1ENSG0000015751031


Protein motifs (from Interpro)
Interpro ID Name
 IPR001849  Pleckstrin homology domain
 IPR011993  PH-like domain superfamily
 IPR030113  Actin-filament associated protein
 IPR030115  Actin filament-associated protein 1-like 2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006954 inflammatory response IDA
 biological_processGO:0007346 regulation of mitotic cell cycle IDA
 biological_processGO:0009966 regulation of signal transduction IEA
 biological_processGO:0009967 positive regulation of signal transduction IEA
 biological_processGO:0032675 regulation of interleukin-6 production IDA
 biological_processGO:0032757 positive regulation of interleukin-8 production IDA
 biological_processGO:0045742 positive regulation of epidermal growth factor receptor signaling pathway IDA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IDA
 biological_processGO:0061098 positive regulation of protein tyrosine kinase activity IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0005886 plasma membrane IDA
 molecular_functionGO:0017124 SH3 domain binding IPI
 molecular_functionGO:0030296 protein tyrosine kinase activator activity IDA
 molecular_functionGO:0035591 signaling adaptor activity IEA
 molecular_functionGO:0042169 SH2 domain binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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