ENSG00000169189


Homo sapiens

Features
Gene ID: ENSG00000169189
  
Biological name :NSMCE1
  
Synonyms : NSE1 homolog, SMC5-SMC6 complex component / NSMCE1 / Q8WV22
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 16
Strand: -1
Band: p12.1
Gene start: 27224991
Gene end: 27268794
  
Corresponding Affymetrix probe sets: 224666_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000458859
Ensembl peptide - ENSP00000456754
Ensembl peptide - ENSP00000457893
Ensembl peptide - ENSP00000355077
Ensembl peptide - ENSP00000454726
Ensembl peptide - ENSP00000455237
Ensembl peptide - ENSP00000456053
Ensembl peptide - ENSP00000456103
NCBI entrez gene - 197370     See in Manteia.
OMIM - 617263
RefSeq - XM_017023042
RefSeq - NM_145080
RefSeq - XM_006721023
RefSeq - XM_011545761
RefSeq - XM_011545762
RefSeq - XM_017023040
RefSeq - XM_017023041
RefSeq Peptide - NP_659547
swissprot - Q8WV22
swissprot - H3BR31
swissprot - H3BR73
swissprot - H3BSL0
swissprot - H3BV05
swissprot - I3L1I3
swissprot - H3BN81
Ensembl - ENSG00000169189
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 nsmce1ENSDARG00000098780Danio rerio
 NSMCE1ENSGALG00000006307Gallus gallus
 Nsmce1ENSMUSG00000030750Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001841  Zinc finger, RING-type
 IPR002219  Protein kinase C-like, phorbol ester/diacylglycerol-binding domain
 IPR011513  Non-structural maintenance of chromosomes element 1
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR014857  Zinc finger, RING-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000724 double-strand break repair via homologous recombination IBA
 biological_processGO:0006281 DNA repair IEA
 biological_processGO:0006301 postreplication repair IBA
 biological_processGO:0006310 DNA recombination IEA
 biological_processGO:0006974 cellular response to DNA damage stimulus IEA
 biological_processGO:0016567 protein ubiquitination IEA
 biological_processGO:0035556 intracellular signal transduction IEA
 biological_processGO:2001022 positive regulation of response to DNA damage stimulus IMP
 cellular_componentGO:0000781 chromosome, telomeric region IEA
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005694 chromosome IEA
 cellular_componentGO:0030915 Smc5-Smc6 complex IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IDA
 molecular_functionGO:0004842 ubiquitin-protein transferase activity IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0046983 protein dimerization activity IDA


Pathways (from Reactome)
Pathway description
SUMOylation of DNA damage response and repair proteins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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