ENSG00000169223


Homo sapiens

Features
Gene ID: ENSG00000169223
  
Biological name :LMAN2
  
Synonyms : lectin, mannose binding 2 / LMAN2 / Q12907
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 5
Strand: -1
Band: q35.3
Gene start: 177331562
Gene end: 177351852
  
Corresponding Affymetrix probe sets: 200805_at (Human Genome U133 Plus 2.0 Array)   215656_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000303366
Ensembl peptide - ENSP00000427377
Ensembl peptide - ENSP00000425229
Ensembl peptide - ENSP00000424132
Ensembl peptide - ENSP00000423998
NCBI entrez gene - 10960     See in Manteia.
OMIM - 609551
RefSeq - NM_006816
RefSeq Peptide - NP_006807
swissprot - D6RBH1
swissprot - D6RIU4
swissprot - Q12907
swissprot - D6RDX1
swissprot - D6RBV2
Ensembl - ENSG00000169223
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 lman2ENSDARG00000061854Danio rerio
 LMAN2ENSGALG00000033232Gallus gallus
 Lman2ENSMUSG00000021484Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
LMAN2L / Q9H0V9 / lectin, mannose binding 2 likeENSG0000011498853
LMAN1 / P49257 / lectin, mannose binding 1ENSG0000007469528
LMAN1L / Q9HAT1 / lectin, mannose binding 1 likeENSG0000014050625


Protein motifs (from Interpro)
Interpro ID Name
 IPR005052  Legume-like lectin
 IPR013320  Concanavalin A-like lectin/glucanase domain superfamily
 IPR035664  VIP36, lectin domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006890 retrograde vesicle-mediated transport, Golgi to ER IMP
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0050766 positive regulation of phagocytosis IEA
 cellular_componentGO:0000139 Golgi membrane IEA
 cellular_componentGO:0005615 extracellular space IDA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane IEA
 cellular_componentGO:0005793 endoplasmic reticulum-Golgi intermediate compartment IDA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005887 integral component of plasma membrane IDA
 cellular_componentGO:0009986 cell surface IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005537 mannose binding IMP
 molecular_functionGO:0030246 carbohydrate binding IEA
 molecular_functionGO:0031072 heat shock protein binding IPI
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
COPII-mediated vesicle transport
Cargo concentration in the ER


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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